Differential susceptibility of retinal ganglion cell subtypes against neurodegenerative diseases

N Zhang, X He, Y Xing, N Yang - Graefe's Archive for Clinical and …, 2022 - Springer
Retinal ganglion cells (RGCs) are essential to propagate external visual information from the
retina to the brain. Death of RGCs is speculated to be closely correlated with blinding retinal …

Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence

C Hu, Y Feng, G Huang, K Cui, M Fan… - Journal of Pineal …, 2024 - Wiley Online Library
Normal tension glaucoma (NTG) is referred to as a progressive degenerative disorder of the
retinal ganglion cells (RGCs), resulting in nonreversible visual defects, despite intraocular …

Melatonin, circadian rhythms and glaucoma: Current perspective

D Gubin, D Weinert - Neural Regeneration Research, 2022 - journals.lww.com
Primary open-angle glaucoma as a causal factor for circadian disruption: Living by the clock,
in alignment with external time cues is an important condition for human health and well …

PEDF-Mediated Mitophagy Triggers the Visual Cycle by Enhancing Mitochondrial Functions in a H2O2-Injured Rat Model

JY Kim, S Park, HJ Park, SH Kim, H Lew, GJ Kim - Cells, 2021 - mdpi.com
Retinal degenerative diseases result from oxidative stress and mitochondrial dysfunction,
leading to the loss of visual acuity. Damaged retinal pigment epithelial (RPE) and …

Contributions of Brain Microstructures and Metabolism to Visual Field Loss Patterns in Glaucoma Using Archetypal and Information Gain Analyses

Y Pang, JW Bang, A Kasi, J Li, C Parra… - … & Visual Science, 2024 - iovs.arvojournals.org
Purpose: To investigate the contributions of the microstructural and metabolic brain
environment to glaucoma and their association with visual field (VF) loss patterns by using …

Chronic restraint stress–induced depression-like behavior is mediated by upregulation of melanopsin expression in C57BL/6 mice retina

Y Fu, S Liu, Y Dong, Y Gan, X Guo, H Liu, Q Xu… - …, 2023 - Springer
Background Depression is associated with circadian disturbances in which melanopsin was
a key mechanism. Further studies have demonstrated that melanopsin gene variations are …

[PDF][PDF] From visual disorder to mental disturbance: How does glaucoma disrupt circadian rhythm?

Y Tang, J Shi, LH Chen, QH Liu, XL Yao - Life Research, 2022 - tmrjournals.com
Clinically, glaucoma patients often suffer from circadian rhythm (CR) disorder. It is well-
known that the imbalance of CR can be one of the triggering mechanisms of glaucoma …

褪黑激素可改善青光眼的昼夜节律紊乱

D Gubin, D Weinert - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Living by the clock, in alignment with external time cues is an important condition for human
health and well-being. Periodic changes in the ambient light serve as a key factor to …

Individualized Modeling and Synchronization of Circadian Oscillators with Light-Dark Cycle

J Yin, J Ma, C He, J Gong, Z Liang… - 2023 9th International …, 2023 - ieeexplore.ieee.org
Sleep behaviors, including daily spontaneous sleep duration, onset, and recovery sleep
duration after sleep deprivation, vary between individuals. Lighting impacts on circadian …