Alternatives to efficient viral vectors in gene therapy are desired because of their poor safety
profiles. Chitosan is a promising non-viral nucleotide delivery vector because of its …

Conventional gene delivery with viral or lipid carriers-are plagued by disadvantages such as
low transfection efficiency, cytotoxicity and immunogenicity. Numerous techniques are being …

Over the last few years, more and more papers have been devoted to phosphorus-
containing polymers, mainly due to their fire resistance, excellent chelating and metal …

Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

Non-viral gene delivery vectors are emerging as a safer alternative to viral vectors. Among
natural polymers, chitosan (Ch) is the most studied one, and low molecular weight Ch …

Chitosan was partially converted to its chlorohydrin derivative by the reaction with
epichlohydrin, which was subsequently reacted with varying amounts of lPEI (2.5 kD) to …

Spray–freeze drying (SFD) is an attractive technique to prepare highly porous dry powders
for inhalation. However, there have been few reports of its application to dry powder inhalers …

Despite multitude of beneficial features, chitosan has poor water solubility and transfection
ability which affect its gene delivery efficacy. The two features are improved when certain …

Biodegradable poly (lactic-co-glycolic acid)(PLGA 50: 50) nanoparticles (NPs) were
prepared and characterized in terms of size, composition, zeta potential and colloidal …

In this study, the antifungal activity of chitosan derivatives against A. flavus was studied to
understand the contribution of the molecular mass (Mw) and of the hydrophobic and …