Uses and challenges of antiviral polyclonal and monoclonal antibody therapies

EB Struble, JMO Rawson, T Stantchev, D Scott… - Pharmaceutics, 2023 - mdpi.com
Viral diseases represent a major public health concerns and ever-present risks for
developing into future pandemics. Antiviral antibody therapeutics, either alone or in …

[PDF][PDF] Marburg virus disease-a mini-review.

S Chakraborty, D Chandran, RK Mohapatra… - 2022 - academia.edu
Marburg virus disease (MVD) is a highly fatal disease caused by the Marburg virus (MARV)
which belongs to the family Filoviridae. The disease has been recently reported from Ghana …

No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model

DS Reed, AK McElroy, DJ Barbeau, CM McMillen… - PLOS …, 2024 - journals.plos.org
Since SARS-CoV-2 emerged in late 2019, it spread from China to the rest of the world. An
initial concern was the potential for vaccine-or antibody-dependent enhancement (ADE) of …

[HTML][HTML] SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity

EJ Martinez, WC Chang, WH Chen, A Hajduczki… - iScience, 2024 - cell.com
The rapid emergence of SARS-CoV-2 variants of concern (VoC) and the threat of future
zoonotic sarbecovirus spillover emphasizes the need for broadly protective next-generation …

Comparison of neutralization potency across passive immunotherapy approaches as potential treatments for emerging infectious diseases

H Ranjbaran, Y Ehteshaminia, M Nadernezhad… - Heliyon, 2024 - cell.com
The use of passive immunotherapy, either as plasma or purified antibodies, has been
recommended to treat the emerging infectious diseases (EIDs) in the absence of alternative …

No evidence for enhanced disease with polyclonal SARS-CoV-2 antibody in the ferret model

DS Reed, AK McElroy, DJ Barbeau, CM McMillen… - bioRxiv, 2023 - biorxiv.org
Since SARS-CoV-2 emerged in late 2019, it spread from China to the rest of the world. An
initial concern was the potential for vaccine-or antibody-enhanced disease (AED) as had …

A Drug-Virus Prediction Model Based on an Ensemble Classifier with Feature Optimization: A Case Study with COVID-19

AS Aruna, KRR Babu, K Deepthi - International Conference on …, 2023 - Springer
Effective therapeutics are still unavailable for the contagious COVID-19, which originated in
Wuhan in December 2019. It is induced by the newly emerged severe acute respiratory …

Computational Discovery of Potential Drug Candidates from Phytochemicals of Withania somnifera and Saraca asoca Targeting Ebola and Marburg Viruses Infection

M Ibrahim, A Detroja, A Bhimani, TC Bhatt, AK Bishoyi… - 2024 - researchsquare.com
Ebola and Marburg viruses are extremely lethal and cause hemorrhagic fever, with deaths
from cases exceeding 90%. Currently, just a few licensed drugs for these diseases. This …