Role of the prefrontal cortex in pain processing

WY Ong, CS Stohler, DR Herr - Molecular neurobiology, 2019 - Springer
The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …

Neocortical circuits in pain and pain relief

LL Tan, R Kuner - Nature Reviews Neuroscience, 2021 - nature.com
The sensory, associative and limbic neocortical structures play a critical role in shaping
incoming noxious inputs to generate variable pain perceptions. Technological advances in …

Common and stimulus-type-specific brain representations of negative affect

M Čeko, PA Kragel, CW Woo, M López-Solà… - Nature …, 2022 - nature.com
The brain contains both generalized and stimulus-type-specific representations of aversive
events, but models of how these are integrated and related to subjective experience are …

Tsception: Capturing temporal dynamics and spatial asymmetry from EEG for emotion recognition

Y Ding, N Robinson, S Zhang, Q Zeng… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
The high temporal resolution and the asymmetric spatial activations are essential attributes
of electroencephalogram (EEG) underlying emotional processes in the brain. To learn the …

Brain glial activation in fibromyalgia–A multi-site positron emission tomography investigation

DS Albrecht, A Forsberg, A Sandström… - Brain, behavior, and …, 2019 - Elsevier
Fibromyalgia (FM) is a poorly understood chronic condition characterized by widespread
musculoskeletal pain, fatigue, and cognitive difficulties. While mounting evidence suggests a …

The search for pain biomarkers in the human brain

A Mouraux, GD Iannetti - Brain, 2018 - academic.oup.com
Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …

Representation, pattern information, and brain signatures: from neurons to neuroimaging

PA Kragel, L Koban, LF Barrett, TD Wager - Neuron, 2018 - cell.com
Human neuroimaging research has transitioned from mapping local effects to developing
predictive models of mental events that integrate information distributed across multiple …

Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia

AM Pinto, R Geenen, TD Wager, MA Lumley… - Nature Reviews …, 2023 - nature.com
Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other
symptoms, and has a substantial socioeconomic impact. Current biomedical and …

Toward a unified framework for interpreting machine-learning models in neuroimaging

L Kohoutová, J Heo, S Cha, S Lee, T Moon… - Nature protocols, 2020 - nature.com
Abstract Machine learning is a powerful tool for creating computational models relating brain
function to behavior, and its use is becoming widespread in neuroscience. However, these …

Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury

H Wang, XM Zhou, LY Wu, GJ Liu, WD Xu… - Journal of …, 2020 - Springer
Abstract Background Aucubin (Au), an iridoid glycoside from natural plants, has
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …