A systematic review of non-coding RNA therapeutics in early clinical trials: a new perspective against cancer

K Grillone, G Caridà, F Luciano, A Cordua… - Journal of Translational …, 2024 - Springer
Targeting non-coding RNAs (ncRNAs), including microRNAs (miRNAs) and long non-
coding RNAs (lncRNAs), has recently emerged as a promising strategy for treating …

Utilizing non-coding RNA-mediated regulation of ATP binding cassette (ABC) transporters to overcome multidrug resistance to cancer chemotherapy

KKW To, Z Huang, H Zhang, CR Ashby Jr, L Fu - Drug Resistance Updates, 2024 - Elsevier
Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …

Innovative approaches to wound healing: insights into interactive dressings and future directions

R Yadav, R Kumar, M Kathpalia, B Ahmed… - Journal of Materials …, 2024 - pubs.rsc.org
The objective of this review is to provide an up-to-date and all-encompassing account of the
recent advancements in the domain of interactive wound dressings. Considering the gap …

Current progress and outlook of nano-based hydrogel dressings for wound healing

X Zhang, P Wei, Z Yang, Y Liu, K Yang, Y Cheng… - Pharmaceutics, 2022 - mdpi.com
Wound dressing is an important tool for wound management. Designing wound dressings
by combining various novel materials and drugs to optimize the peri-wound environment …

Mitigating off‐target effects of small RNAs: conventional approaches, network theory and artificial intelligence

Z Bereczki, B Benczik, OM Balogh… - British Journal of …, 2025 - Wiley Online Library
Three types of highly promising small RNA therapeutics, namely, small interfering RNAs
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …

Nucleic acid-based therapeutics for dermal wound healing

P Sharma, A Kumar, T Agarwal, AD Dey… - International Journal of …, 2022 - Elsevier
Non-healing wounds have long been the subject of scientific and clinical investigations.
Despite breakthroughs in understanding the biology of delayed wound healing, only limited …

Noncoding RNAs in cardiac hypertrophy and heart failure

P Lu, F Ding, YK Xiang, L Hao, M Zhao - Cells, 2022 - mdpi.com
Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in
physiological processes and in the pathogenesis of various diseases, including heart failure …

Metal-and covalent-organic framework-based drug delivery systems: applications to control cell functions

MJ Kang, YW Cho, TH Kim - Coordination Chemistry Reviews, 2025 - Elsevier
Tissue engineering and regenerative medicine are interdisciplinary fields that aim to repair
structural or functional defects in target tissues by replicating the physiological …

Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases

LA Bravo-Vázquez, S Paul, MG Colín-Jurado… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …

Cardiovascular complications of diabetes: role of non-coding RNAs in the crosstalk between immune and cardiovascular systems

G Spinetti, M Mutoli, S Greco, F Riccio… - Cardiovascular …, 2023 - Springer
Diabetes mellitus, a group of metabolic disorders characterized by high levels of blood
glucose caused by insulin defect or impairment, is a major risk factor for cardiovascular …