Targeting endothelial dysfunction and inflammation

L Wang, CK Cheng, M Yi, KO Lui, Y Huang - Journal of molecular and …, 2022 - Elsevier
Vascular endothelium maintains vascular homeostasis through liberating a spectrum of
vasoactive molecules, both protective and harmful regulators of vascular tone, structural …

Analysis of association between vitamin D deficiency and insulin resistance

I Szymczak-Pajor, A Śliwińska - Nutrients, 2019 - mdpi.com
Recent evidence revealed extra skeleton activity of vitamin D, including prevention from
cardiometabolic diseases and cancer development as well as anti-inflammatory properties …

Endothelial dysfunction and vascular disease–a 30th anniversary update

PM Vanhoutte, H Shimokawa, M Feletou… - Acta …, 2017 - Wiley Online Library
The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

The molecular mechanisms by which vitamin D prevents insulin resistance and associated disorders

I Szymczak-Pajor, J Drzewoski, A Śliwińska - International journal of …, 2020 - mdpi.com
Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …

[HTML][HTML] Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial …

C Cui, P Xu, G Li, Y Qiao, W Han, C Geng, D Liao… - Redox biology, 2019 - Elsevier
Hypertension is one of the major predisposing factors for neurodegenerative disease
characterized with activated renin-angiotensin system (RAS) in both periphery and brain …

Role of vitamin D deficiency in the pathogenesis of cardiovascular and cerebrovascular diseases

É Pál, Z Ungvári, Z Benyó, S Várbíró - Nutrients, 2023 - mdpi.com
Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects
approximately 24% to 40% of the population of the Western world. In addition to its well …

Sunlight and Vitamin D: A global perspective for health

M Wacker, MF Holick - Dermato-endocrinology, 2013 - Taylor & Francis
Vitamin D is the sunshine vitamin that has been produced on this earth for more than 500
million years. During exposure to sunlight 7-dehydrocholesterol in the skin absorbs UV B …

Role of vitamin D beyond the skeletal function: a review of the molecular and clinical studies

M Umar, KS Sastry, AI Chouchane - International journal of molecular …, 2018 - mdpi.com
The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

Vitamin D deficiency and diabetes

MJ Berridge - Biochemical Journal, 2017 - portlandpress.com
Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Effects of vitamin D on cardiovascular risk and oxidative stress

G Renke, B Starling-Soares, T Baesso, R Petronio… - Nutrients, 2023 - mdpi.com
Introduction: Vitamin D has been primarily studied as an important factor influencing bone
and calcium metabolism. Metabolites of vitamin D are essential for whole-body calcium …