Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment

P Sarzi-Puttini, V Giorgi, D Marotto… - Nature Reviews …, 2020 - nature.com
Fibromyalgia is characterized by chronic widespread pain, fatigue, sleep disturbances and
functional symptoms. The etiopathogenesis, diagnostic criteria and classification criteria of …

[HTML][HTML] AAPT diagnostic criteria for fibromyalgia

LM Arnold, RM Bennett, LJ Crofford, LE Dean… - The journal of pain, 2019 - Elsevier
Fibromyalgia (FM) is a common chronic pain disorder that presents diagnostic challenges
for clinicians. Several classification, diagnostic and screening criteria have been developed …

The neurobiology of central sensitization

SE Harte, RE Harris, DJ Clauw - Journal of Applied …, 2018 - Wiley Online Library
Central sensitization refers to the amplification of pain by central nervous system
mechanisms. Classically described as a consequence of ongoing nociceptive input, it is …

[HTML][HTML] Mechanisms and pathways of pain photobiomodulation: a narrative review

K Cheng, LF Martin, MJ Slepian, AM Patwardhan… - The journal of pain, 2021 - Elsevier
A growing body of evidence supports the modulation of pain by light exposure. As such,
phototherapy is being increasingly utilized for the management of a variety of pain …

Long-lasting antinociceptive effects of green light in acute and chronic pain in rats

MM Ibrahim, A Patwardhan, KB Gilbraith, A Moutal… - Pain, 2017 - journals.lww.com
Treatments for chronic pain are inadequate, and new options are needed.
Nonpharmaceutical approaches are especially attractive with many potential advantages …

Functional and neurochemical disruptions of brain hub topology in chronic pain

CM Kaplan, A Schrepf, D Vatansever, TE Larkin… - Pain, 2019 - journals.lww.com
A critical component of brain network architecture is a robust hub structure, wherein hub
regions facilitate efficient information integration by occupying highly connected and …

Parabrachial complex links pain transmission to descending pain modulation

Z Roeder, QL Chen, S Davis, JD Carlson, D Tupone… - Pain, 2016 - journals.lww.com
The rostral ventromedial medulla (RVM) has a well-documented role in pain modulation and
exerts antinociceptive and pronociceptive influences mediated by 2 distinct classes of …

Increased sleep disturbances and pain in veterans with comorbid traumatic brain injury and posttraumatic stress disorder

NM Balba, JE Elliott, KB Weymann, RA Opel… - Journal of Clinical …, 2018 - jcsm.aasm.org
Study Objectives: Veterans are at an increased risk for traumatic brain injury (TBI) and
posttraumatic stress disorder (PTSD), both of which are associated with sleep disturbances …

Shifting the Balance: How Top-Down and Bottom-Up Input Modulate Pain via the Rostral Ventromedial Medulla

Q Chen, MM Heinricher - Frontiers in Pain Research, 2022 - frontiersin.org
The sensory experience of pain depends not only on the transmission of noxious information
(nociception), but on the state of the body in a biological, psychological, and social milieu. A …

Pharmacologic attenuation of cross-modal sensory augmentation within the chronic pain insula

SE Harte, E Ichesco, JP Hampson, SJ Peltier… - Pain, 2016 - journals.lww.com
Pain can be elicited through all mammalian sensory pathways yet cross-modal sensory
integration, and its relationship to clinical pain, is largely unexplored. Centralized chronic …