Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …

Current tuberculosis (TB) drug development efforts are not sufficient to end the global TB
epidemic. Recent efforts have focused on the development of whole-cell screening assays …

The capacity of Mycobacterium tuberculosis (Mtb) to tolerate multiple antibiotics represents a
major problem in tuberculosis (TB) management. Heterogeneity in Mtb populations is one of …

The generation of phagosomal cytotoxic reactive species (ie, free radicals and oxidants) by
activated macrophages and neutrophils is a crucial process for the control of intracellular …

Mycobacterium tuberculosis (Mtb) senses and adapts to acidic host environments during the
course of pathogenesis. Mutants defective in acidic pH-dependent adaptations are often …

Mycobacterium tuberculosis (Mtb) employs plethora of mechanisms to hijack the host
defence machinery for its successful survival, proliferation and persistence. Here, we show …

Summary The WhiB‐like (Wbl) family of proteins are exclusively found in Actinobacteria.
Wbls have been shown to play key roles in virulence and antibiotic resistance in …

Low molecular weight (LMW) thiols contain reducing sulfhydryl groups that are important for
maintaining antioxidant defense in the cell. Aside from the traditional roles of LMW thiols as …

Mycobacterium tuberculosis (Mtb) drug resistance poses an alarming threat to global
tuberculosis control. We previously reported that C10, a ring-fused thiazolo-2-pyridone …

Transcriptional reprogramming of macrophages upon Mycobacterium tuberculosis (Mtb)
infection is widely studied; however, the significance of alternate splicing (AS) in shaping …