Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Curcumin‐piperine co‐supplementation and human health: a comprehensive review of preclinical and clinical studies

H Heidari, M Bagherniya, M Majeed… - Phytotherapy …, 2023 - Wiley Online Library
Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐
inflammatory and anti‐oxidant activities. Despite its safety and potential for use against …

[HTML][HTML] The effect of curcumin on cognition in Alzheimer's disease and healthy aging: A systematic review of pre-clinical and clinical studies

SD Voulgaropoulou, T Van Amelsvoort, J Prickaerts… - Brain research, 2019 - Elsevier
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging
population. Given that current treatments do not produce the desired therapeutic effects, the …

Therapeutic effects of turmeric in several diseases: An overview

E Hay, A Lucariello, M Contieri, T Esposito… - Chemico-biological …, 2019 - Elsevier
A nutraceutical product can be defined as a substance that has a physiological benefit or
provides protection against chronic diseases. The term nutraceutical is a hybrid term derived …

Neuroprotective effect of curcumin on the nigrostriatal pathway in a 6-hydroxydopmine-induced rat model of Parkinson's disease is mediated by α7-nicotinic receptors

E El Nebrisi, H Javed, SK Ojha, M Oz… - International journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by
selective degeneration of dopaminergic nigrostriatal neurons. Most of the existing …

Apigenin attenuates functional and structural alterations via targeting NF-kB/Nrf2 signaling pathway in LPS-induced parkinsonism in experimental rats: Apigenin …

M Patel, S Singh - Neurotoxicity Research, 2022 - Springer
Parkinson's disease (PD) is a progressive hypokinetic movement disorder caused by
selective degeneration of dopaminergic neurons in striatum and dopamine deficiency in a …

Characteristics, biological properties and analytical methods of piperine: A review

CR Quijia, M Chorilli - Critical reviews in analytical chemistry, 2020 - Taylor & Francis
Piperine (PIP) is a natural alkaloid isolated from Piper longum L. that presents antioxidant,
anticonvulsant, antimicrobial, neuroprotective, larvicidal, antiparasitic, anticancer effect and …

Improved solubility and dissolution rates in novel multicomponent crystals of piperine with succinic acid

E Zaini, Afriyani, L Fitriani, F Ismed, A Horikawa… - Scientia …, 2020 - mdpi.com
The objectives of this study were to prepare and characterize a novel piperine–succinic acid
multicomponent crystal phase and to evaluate the improvement in the solubility and …

Relationship of curcumin with aging and Alzheimer and Parkinson disease, the most prevalent age-related neurodegenerative diseases: a narrative review

BY Turer, N Sanlier - Nutrition Reviews, 2024 - academic.oup.com
The elderly population is increasing worldwide every day. Age is a significant factor in the
progression of neurological diseases, which can also cause cognitive decline and memory …

Piperine: Chemical, biological and nanotechnological applications

CR Quijia, VH Araujo, M Chorilli - Acta pharmaceutica, 2021 - hrcak.srce.hr
Sažetak Piperine (PIP) is an alkaloid present in several species of piper, mainly Piper
nigrum Linn. and P. longum, among other species. The present article provides a …