Adult stem cells constitute an important reservoir of self-renewing progenitor cells and are
crucial for maintaining tissue and organ homeostasis. The capacity of stem cells to self …

Advanced age is a shared risk factor for many chronic and debilitating skeletal diseases
including osteoporosis and periodontitis. Mesenchymal stem cells develop various aging …

Hematopoietic stem cells (HSCs) rely on complex regulatory networks to preserve stemness.
Due to the scarcity of HSCs, technical challenges have limited our insights into the interplay …

A broad range of data identify Ca2+-permeable amyloid pores as the most neurotoxic
species of Alzheimer's β-amyloid peptide (Aβ1–42). Following the failures of clinical trials …

Mesenchymal stem cells (MSCs) are of great interest for their use in cell-based therapies
due to their multipotent differentiation and immunomodulatory capacities. In consequence of …

Osteoporosis (OP) is a systemic disease characterized by bone metabolism imbalance and
bone microstructure destruction, which causes serious social and economic burden. At …

Lipids are critical structural and functional architects of cellular homeostasis. Change in
systemic lipid profile is a clinical indicator of underlying metabolic pathologies, and …

This paper reviews the application of metabolomics in the early diagnosis of osteoporosis in
recent years. The authors searched electronic databases for the keywords “metabolomics”,“ …

Mesenchymal stem cells (MSCs) have become popular tool cells in the field of
transformation and regenerative medicine due to their function of cell rescue and cell …

This paper describes, for the first time to our knowledge, a lipidome and exometabolome
characterization of osteogenic differentiation for human adipose tissue stem cells (hAMSCs) …