Oxidative stress (OS) arises when the body is subjected to harmful endogenous or
exogenous factors that overwhelm the antioxidant system. There is increasing evidence that …

Ovarian cancer is a common gynecological malignancy, and its treatment remains
challenging. Although ovarian cancer may respond to immunotherapy because of …

Anti-cancer medications that are delivered specifically to the tumor site possess greater
efficacy with less negative effects on the body. So, the current research relies on a novel …

Aim: The aim of the present investigation was to develop niosomes containing both
curcumin (CUR) and methotrexate (MTX). Also, the combinational effect of CUR and MTX in …

Purine, an abundant substrate in organisms, is a critical raw material for cell proliferation
and an important factor for immune regulation. The purine de novo pathway and salvage …

The phenolic and flavonoid content of the Stevia rebaudiana hydromethanolic extract
(SRHME) was examined, and phytochemical identification using GC‐mass spectrometry …

Amifostine is used in chemotherapy and radiotherapy as a cytoprotective adjuvant alongside
DNA-binding chemotherapeutic agents. It functions by reducing free radicals and detoxifying …

Methotrexate (MTX) is frequently used drug in treatment of cancer and autoimmune
diseases. Unfortunately, MTX has many side effects including the hepato-renal toxicity. In …

Abstract Di (2-ethylhexyl) phthalate (DEHP), a widely spreading environmental endocrine
disruptor, has been confirmed to adversely affect the development of animals and humans …

Oxidative stress refers to the imbalance between the production of reactive oxygen species
(ROS) and the endogenous antioxidant defense system. Its involvement in cell senescence …