Gastrointestinal involvement in Parkinson's disease: pathophysiology, diagnosis, and management

T Warnecke, KH Schäfer, I Claus, K Del Tredici… - npj Parkinson's …, 2022 - nature.com
Growing evidence suggests an increasing significance for the extent of gastrointestinal tract
(GIT) dysfunction in Parkinson's disease (PD). Most patients suffer from GIT symptoms …

Neurogenic dysphagia: systematic review and proposal of a classification system

T Warnecke, B Labeit, J Schroeder, A Reckels… - Neurology, 2021 - AAN Enterprises
Objective Introduction and validation of a phenotypic classification of neurogenic dysphagia
based on flexible endoscopic evaluation of swallowing (FEES). Methods A systematic …

Expiratory muscle strength training for therapy of pharyngeal dysphagia in Parkinson's disease

I Claus, P Muhle, J Czechowski, S Ahring… - Movement …, 2021 - Wiley Online Library
Abstract Background Pharyngeal dysphagia in Parkinson's disease (PD) is a common and
clinically relevant symptom associated with poor nutrition intake, reduced quality of life, and …

[HTML][HTML] Consensus on the treatment of dysphagia in Parkinson's disease

A Schindler, N Pizzorni, E Cereda, G Cosentino… - Journal of the …, 2021 - Elsevier
Background Dysphagia is common in Parkinson's disease (PD). The effects of
antiparkinsonian drugs on dysphagia are controversial. Several treatments for dysphagia …

[HTML][HTML] Comparison of simultaneous swallowing endoscopy and videofluoroscopy in neurogenic dysphagia

B Labeit, S Ahring, M Boehmer, P Sporns… - Journal of the American …, 2022 - Elsevier
Objective In the evaluation of oropharyngeal dysphagia, instrumental procedures, for
example, flexible endoscopic evaluation of swallowing or videofluoroscopic swallowing …

Does gut brain axis has an impact on Parkinson's disease (PD)?

A Elangovan, B Dahiya, L Kirola, M Iyer, P Jeeth… - Ageing Research …, 2024 - Elsevier
Parkinson's Disease (PD) is becoming a growing global concern by being the second most
prevalent disease next to Alzheimer's Disease (AD). Henceforth new exploration is needed …

Validation of the DIGEST-FEES as a global outcome measure for pharyngeal dysphagia in Parkinson's disease

B Labeit, S Lapa, P Muhle, S Suntrup-Krueger, I Claus… - Dysphagia, 2024 - Springer
Abstract Flexible Endoscopic Evaluation of Swallowing (FEES) is one of two diagnostic gold
standards for pharyngeal dysphagia in Parkinson's disease (PD), however, validated global …

Management of dysphagia and gastroparesis in Parkinson's disease in real-world clinical practice–Balancing pharmacological and non-pharmacological approaches

R Bhidayasiri, W Phuenpathom, AH Tan… - Frontiers in Aging …, 2022 - frontiersin.org
Gastrointestinal (GI) issues are commonly experienced by patients with Parkinson's disease
(PD). Those that affect the lower GI tract, such as constipation, are the most frequently …

New and evolving treatments for neurologic dysphagia

A Sasegbon, I Cheng, B Labeit, S Lapa, N Rommel… - Drugs, 2024 - Springer
Despite swallowing being a frequently performed daily function, it is highly complex. For a
safe swallow to occur, muscles within the head, neck, and thorax need to contract in a …

rTMS improves dysphagia by inhibiting NLRP3 inflammasome activation and caspase-1 dependent pyroptosis in PD mice

P Huang, Z Zhu, W Li, R Zhang, Y Chi… - npj Parkinson's …, 2024 - nature.com
High incidence, severe consequences, unclear mechanism, and poor treatment effect
happened in Parkinson's disease-related dysphagia. Repetitive transcranial magnetic …