It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

A new optically active BINOL-amino alcohol has been designed and synthesized in a good
yield and applied as chiral nuclear magnetic resonance (NMR) solvating agent for …

The development of molecular probes for optical sensing of chiral compounds has received
increasing attention in recent years, in particular because of the potential to accelerate …

Abstract Ethyl (R)-4-chloro-3-hydroxybutyrate ((R)-CHBE) is a versatile fine chemistry
intermediate. It is used as a precursor in the synthesis of several pharmacologically valuable …

Abstract Design of the reversible biphasic system for a practical use in asymmetric
hydrogenation performed in a microfluidic chip reactor is reported. Methylacetoacetate …

Enantiomeric purity control is a must when working with chiral drugs. In this context,
homochiral cycles consisting solely of 1 to 3 binaphthalene units interconnected with urea …

Over 85% of small molecule pharmaceuticals approved by the FDA in 2019 contained a
nitrogen-based heterocycle and over a quarter of all FDA approved drugs on the market …