NMR as a “gold standard” method in drug design and discovery
Studying disease models at the molecular level is vital for drug development in order to
improve treatment and prevent a wide range of human pathologies. Microbial infections are …
improve treatment and prevent a wide range of human pathologies. Microbial infections are …
Synthesis and biological evaluation of novel aryloxyacetic acid hydrazide derivatives as anticancer agents
In our continuing search for new anticancer agents, herein we report the synthesis of 2-(4-
chloro-3-methylphenoxy)-N'-[(aryl) methylidene] acetohydrazides 3a–j and the evaluation of …
chloro-3-methylphenoxy)-N'-[(aryl) methylidene] acetohydrazides 3a–j and the evaluation of …
Employing molecular dynamics simulations and DFT calculations to elucidate the energetic, structural, and spectroscopic attributes of (poly) valines in water solution
RC Prado, K Mendanha, LBA Oliveira… - Chemical Physics …, 2024 - Elsevier
In this study, we explored how the growth of peptide chains containing valines impacts
nuclear magnetic resonance (NMR) and optical absorption spectra. Results stem from …
nuclear magnetic resonance (NMR) and optical absorption spectra. Results stem from …
Synthesis, Structure Elucidation and Biological Activity of New Hybrid Hydrazone-Amide Compounds
Bacterial infection today occupies a tremendous place in world health. The infection
diseases were kept under control after the development of penicillin and further studies were …
diseases were kept under control after the development of penicillin and further studies were …