Difficulties in recruiting older people in clinical trials: an examination of barriers and solutions

I Ridda, CR MacIntyre, RI Lindley, TC Tan - Vaccine, 2010 - Elsevier
Limited information exists regarding optimal methods for the recruitment and retention of
older people in clinical trials. The aim of this review is to identify common barriers to the …

Is exercise an acceptable and practical therapy for people with or cured of cancer? A systematic review

M Maddocks, S Mockett, A Wilcock - Cancer treatment reviews, 2009 - Elsevier
INTRODUCTION: Therapeutic exercise, although potentially beneficial, does not appear
acceptable to many cancer patients. A greater understanding of the reasons for this is …

Clinical trial enrollment, patient characteristics, and survival differences in prospectively registered metastatic colorectal cancer patients

H Sorbye, P Pfeiffer, N Cavalli‐Björkman, C Qvortrup… - Cancer, 2009 - Wiley Online Library
BACKGROUND: Trial accrual patterns were examined to determine whether metastatic
colorectal cancer (mCRC) patients enrolled in trials are representative of a general cancer …

Inviting parents to take part in paediatric palliative care research: a mixed-methods examination of selection bias

JC Crocker, E Beecham, P Kelly… - Palliative …, 2015 - journals.sagepub.com
Background: Recruitment to paediatric palliative care research is challenging, with high
rates of non-invitation of eligible families by clinicians. The impact on sample characteristics …

The challenges of clinical trials in the exclusion zone: the case of the frail elderly

I Ridda, R Lindley, RC MacIntyre - Australasian journal on …, 2008 - Wiley Online Library
Frail older people have been systematically excluded from randomised controlled trials
(RCT). We aim to recruit older, frail hospitalised patients in an RCT and evaluate the frailty …

From information processing to behavioral intentions: Exploring cancer patients' motivations for clinical trial enrollment

ZJ Yang, K McComas, G Gay, JP Leonard… - Patient Education and …, 2010 - Elsevier
OBJECTIVE: To investigate cancer patients' motivations for clinical trial enrollment, this study
tests the proposition that a model of Risk Information Seeking and Processing (RISP) could …

Maximising recruitment into randomised controlled trials: the role of multidisciplinary cancer teams

AGK McNair, CTP Choh, C Metcalfe… - European journal of …, 2008 - Elsevier
Multidisciplinary cancer teams offer many theoretical benefits, although few have been
formally examined. This study evaluated the role of multidisciplinary team (MDT) meetings in …

Barriers and challenges to global clinical cancer research

B Seruga, A Sadikov, EL Cazap, LB Delgado… - The …, 2014 - academic.oup.com
Background. There are concerns about growing barriers to cancer research. We explored
the characteristics of and barriers to global clinical cancer research. Methods. The American …

How are we communicating about clinical trials?: an assessment of the content and readability of recruitment resources

DB Friedman, SH Kim, A Tanner, CD Bergeron… - Contemporary clinical …, 2014 - Elsevier
Clinical trials (CTs) are important for advancing public health and medical research,
however, CT recruitment is challenging. The high reading level of CT information and the …

Timing of palliative care referral and symptom burden in phase 1 cancer patients: A retrospective cohort study

D Hui, H Parsons, L Nguyen, SL Palla… - Cancer, 2010 - Wiley Online Library
BACKGROUND: Phase 1 trials offer patients with advanced cancer the opportunity to pursue
life‐prolonging cancer treatments. In the current study, the timing of referral and symptom …