Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy

X Zheng, X Jin, F Ye, X Liu, B Yu, Z Li, T Zhao… - … Hematology & Oncology, 2023 - Springer
Background Ferroptosis is a regulated cell death mode triggered by iron-dependent toxic
membrane lipid peroxidation. As a novel cell death modality that is morphologically and …

Molecular mechanisms of ferroptosis and updates of ferroptosis studies in cancers and leukemia

H Akiyama, BZ Carter, M Andreeff, J Ishizawa - Cells, 2023 - mdpi.com
Ferroptosis is a mode of cell death regulated by iron-dependent lipid peroxidation. Growing
evidence suggests ferroptosis induction as a novel anti-cancer modality that could …

Hydnocarpin D attenuates lipopolysaccharide-induced acute lung injury via MAPK/NF-κB and Keap1/Nrf2/HO-1 pathway

H Hong, S Lou, F Zheng, H Gao, N Wang, S Tian… - Phytomedicine, 2022 - Elsevier
Background Acute lung injury (ALI) is a complex pulmonary destructive disease with limited
therapeutic approaches. Hydnocarpin D (HD) is a flavonolignan isolated from Hydnocarpus …

Molecular mechanisms of ferroptosis and its roles in hematologic malignancies

Y Zhao, Z Huang, H Peng - Frontiers in oncology, 2021 - frontiersin.org
Cell death is essential for the normal metabolism of human organisms. Ferroptosis is a
unique regulated cell death (RCD) mode characterized by excess accumulation of iron …

Unveiling autophagy complexity in leukemia: The molecular landscape and possible interactions with apoptosis and ferroptosis

YY Jung, KS Ahn, M Shen - Cancer Letters, 2024 - Elsevier
Autophagy is a self-digestion multistep process in which causes the homeostasis through
degradation of macromolecules and damaged organelles. The autophagy-mediated tumor …

Ferroptosis in acute leukemia

T Lyu, X Li, Y Song - Chinese Medical Journal, 2023 - mednexus.org
Ferroptosis is an iron-dependent cell death pathway that is different from apoptosis,
pyroptosis, and necrosis. The main characteristics of ferroptosis are the Fenton reaction …

Potential applications of ferroptosis inducers and regulatory molecules in hematological malignancy therapy

X Tang, Y Niu, J Jian, Y Guo, Y Wang, Y Zhu… - Critical Reviews in …, 2024 - Elsevier
Ferroptosis, a novel form of iron-dependent cell death, has emerged as a potential avenue
for promoting tumor cell death by causing cell membrane rupture and the accumulation of …

Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo

X Pei, Z Zhang, N Wang, G Huang, X Min, Y Yang… - Bioorganic …, 2023 - Elsevier
Acute lung injury (ALI) is a devastating respiratory disorder characterized by rapid alveolar
injury, uncontrolled inflammatory response, etc. Onychiol B is a cyathane diterpene …

Ferroptosis in haematological malignancies and associated therapeutic nanotechnologies

RL Mynott, A Habib, OG Best… - International journal of …, 2023 - mdpi.com
Haematological malignancies are heterogeneous groups of cancers of the bone marrow,
blood or lymph nodes, and while therapeutic advances have greatly improved the lifespan …

Molecular mechanisms of ferroptosis and its roles in leukemia

Z Chen, S Zheng, J Han, L Fu, J Fu, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Cell death is a complex process required to maintain homeostasis and occurs when cells
are damage or reach end of life. As research progresses, it is apparent that necrosis and …