The Role of Bacterial Enhancer Binding Proteins as Specialized Activators of σ54-Dependent Transcription

M Bush, R Dixon - Microbiology and Molecular Biology Reviews, 2012 - Am Soc Microbiol
Bacterial enhancer binding proteins (bEBPs) are transcriptional activators that assemble as
hexameric rings in their active forms and utilize ATP hydrolysis to remodel the conformation …

Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology

N Joly, C Engl, G Jovanovic, M Huvet… - FEMS microbiology …, 2010 - academic.oup.com
The bacterial phage shock protein (Psp) response functions to help cells manage the
impacts of agents impairing cell membrane function. The system has relevance to …

Mechanisms of DNA opening revealed in AAA+ transcription complex structures

F Ye, F Gao, X Liu, M Buck, X Zhang - Science Advances, 2022 - science.org
Gene transcription is carried out by RNA polymerase (RNAP) and requires the conversion of
the initial closed promoter complex, where DNA is double stranded, to a transcription …

[HTML][HTML] Mechanisms of σ54-dependent transcription initiation and regulation

AE Danson, M Jovanovic, M Buck, X Zhang - Journal of molecular biology, 2019 - Elsevier
Cellular RNA polymerase is a multi-subunit macromolecular assembly responsible for gene
transcription, a highly regulated process conserved from bacteria to humans. In bacteria …

Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior

C Francke, T Groot Kormelink, Y Hagemeijer… - BMC genomics, 2011 - Springer
Background Sigma-54 is a central regulator in many pathogenic bacteria and has been
linked to a multitude of cellular processes like nitrogen assimilation and important functional …

Regulation of the co-evolved HrpR and HrpS AAA+ proteins required for Pseudomonas syringae pathogenicity

M Jovanovic, EH James, PC Burrows… - Nature …, 2011 - nature.com
The bacterial AAA+ enhancer-binding proteins (EBPs) HrpR and HrpS (HrpRS) of
Pseudomonas syringae (Ps) activate σ54-dependent transcription at the hrpL promoter; …

Mechanisms for activating bacterial RNA polymerase

T Ghosh, D Bose, X Zhang - FEMS microbiology reviews, 2010 - academic.oup.com
Gene transcription is a fundamental cellular process carried out by RNA polymerase (RNAP)
enzymes and is highly regulated through the action of gene regulatory complexes. Important …

Regulation of Type VI Secretion Gene Clusters by σ54 and Cognate Enhancer Binding Proteins

CS Bernard, YR Brunet, M Gavioli, R Lloubes… - Journal of …, 2011 - Am Soc Microbiol
Type VI secretion systems (T6SS) are bacteriophage-derived macromolecular machines
responsible for the release of at least two proteins in the milieu, which are thought to form an …

Signal sensory systems that impact σ54-dependent transcription

V Shingler - FEMS microbiology reviews, 2011 - academic.oup.com
Alternative σ-factors of bacteria bind core RNA polymerase to program the specific promoter
selectivity of the holoenzyme. Signal-responsive changes in the availability of different σ …

Structures of RNA polymerase closed and intermediate complexes reveal mechanisms of DNA opening and transcription initiation

R Glyde, F Ye, VC Darbari, N Zhang, M Buck, X Zhang - Molecular cell, 2017 - cell.com
Gene transcription is carried out by RNA polymerases (RNAPs). For transcription to occur,
the closed promoter complex (RPc), where DNA is double stranded, must isomerize into an …