Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program

MM Wheeler, AM Stilp, S Rao, BV Halldórsson… - Nature …, 2022 - nature.com
Genome-wide association studies have identified thousands of single nucleotide variants
and small indels that contribute to variation in hematologic traits. While structural variants …

Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis

LB Vargas, LA Lange, K Ferrier, F Aguet… - International Journal of …, 2023 - nature.com
Background/objectives Obesity, defined as excessive fat accumulation that represents a
health risk, is increasing in adults and children, reaching global epidemic proportions. Body …

An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling

N Kurniansyah, DA Wallace, Y Zhang, B Yu… - Communications …, 2023 - nature.com
Abstract Sleep Disordered Breathing (SDB) is a common disease associated with increased
risk for cardiometabolic, cardiovascular, and cognitive diseases. How SDB affects the …

Expression patterns of melanin‐related genes are linked to crypsis and conspicuousness in a pumpkin toadlet

JPC Monteiro, H Pröhl, ML Lyra, AE Brunetti… - Molecular …, 2024 - Wiley Online Library
Colour signals play pivotal roles in different communication systems, and the evolution of
these characters has been associated with behavioural ecology, integumentary production …

An integrated multi-omics analysis of sleep-disordered breathing traits across multiple blood cell types

N Kurniansyah, DA Wallace, Y Zhang, B Yu, B Cade… - medRxiv, 2022 - medrxiv.org
ABSTRACT Background Sleep Disordered Breathing (SDB) is characterized by repeated
breathing reductions or cessations during sleep, often accompanied by oxyhemoglobin …