The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …

The efficacy of an antiretroviral (ARV) treatment regimen depends on the activity of the
regimen's individual ARV drugs and the number of HIV-1 mutations required for the …

Context New trial data and drug regimens that have become available in the last 2 years
warrant an update to guidelines for antiretroviral therapy (ART) in human immunodeficiency …

Antiretroviral therapy of HIV infection has changed a uniformly fatal into a potentially chronic
disease. There are now 17 drugs in common use for HIV treatment. Patients who can access …

Context The availability of new antiretroviral drugs and formulations, including drugs in new
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …

HIV protease plays a crucial role in the viral life cycle and is essential for the generation of
mature infectious virus particles. Detailed knowledge of the structure of HIV protease and its …

Lopinavir/ritonavir is the first and only coformulated HIV-1 protease inhibitor (PI). Large
clinical trials have demonstrated lopinavir/ritonavir's clinical efficacy in both antiretroviral …

Background: The present primary analysis of AntiRetroviral Therapy with TMC114 ExaMined
In naive Subjects (ARTEMIS) compares the efficacy and safety of once-daily …

Background To reduce lipid abnormalities and other side-effects associated with
antiretroviral regimens containing lopinavir-ritonavir, patients might want to switch one or …

The article presents guidelines from the British HIV Association for the treatment of HIV-1-
infected adults using antiretroviral therapy. It presents data from clinical trials on the …