There has long been a fascination in the DNA repair pathways of archaea, for two main
reasons. Firstly, many archaea inhabit extreme environments where the rate of physical …

Homologous DNA pairing and strand exchange are at the core of homologous
recombination. These reactions are promoted by a DNA-strand-exchange protein …

Archaea represents the third domain of life, with the information-processing machineries
more closely resembling those of eukaryotes than the machineries of the bacterial …

Natural transformation (NT) in bacteria is a complex process, including binding, uptake,
transport and recombination of exogenous DNA into the chromosome, consequently …

RecA family recombinases play essential roles in maintaining genome integrity. A group of
RecA-like proteins named RadC are present in all archaea, but their in vivo functions remain …

Protein phosphorylation is one of the main protein post-translational modifications and
regulates DNA repair in eukaryotes. Archaeal genomes encode eukaryotic-like DNA repair …

Nanobiomotors perform various important functions in the cell, and they also emerge as
potential vehicle for drug delivery. These proteins employ conserved ATPase domains to …

Repair of DNA double-strand breaks is a critical function shared by organisms in all three
domains of life. The majority of mechanistic understanding of this process has come from …

Homologous recombination (HR) is a major pathway for the repair of double-strand DNA
breaks, a highly deleterious form of DNA damage. The main catalytic protein in HR is the …

Sažetak Oštećenja DNA uzrokovana endogenim i egzogenim čimbenicima utječu na
vijabilnost organizama, a time i na opstanak vrste. Zahvaljujući mnogim mehanizmima …