Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

Skin injuries and in particular, chronic wounds, are one of the major prevalent medical
problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration …

Diabetic foot ulcers are a major health‐care burden worldwide. One primary cause of the
delayed wound healing in diabetic patients is impaired function of the hypoxia‐inducible …

Angiogenesis promotes rejuvenation in multiple organs, including the skin. Heat shock
protein 90 (HSP90), hypoxia-inducible factor-1 alpha (HIF-1α), and vascular endothelial …

Myocardial infarction (MI), an acute cardiovascular disease characterized by coronary artery
blockage, inadequate blood supply, and subsequent ischemic necrosis of the myocardium …

Background: Recent advances in high-throughput single-cell sequencing technologies have
led to their increasingly widespread adoption for clinical applications. However, challenges …

Macrophages are critical mediators of tissue vascularization both in health and disease. In
multiple tissues, macrophages have been identified as important regulators of both blood …

Numerous individuals suffer from impaired wound healing, such as chronic ulcers, severe
burns and immune disorders, resulting in both public health and economic burdens. Skin is …