Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia

Z Mann, F Lim, S Verma, BN Nanavati… - Molecular Biology of …, 2024 - Am Soc Cell Biol
Apical extrusion is a tissue-intrinsic process that allows epithelia to eliminate unfit or surplus
cells. This is exemplified by the early extrusion of apoptotic cells, which is critical to maintain …

[HTML][HTML] Targeting F-actin stress fibers to suppress the dedifferentiated phenotype in chondrocytes

MM Schofield, AT Rzepski… - European journal of cell …, 2024 - Elsevier
Actin is a central mediator of the chondrocyte phenotype. Monolayer expansion of articular
chondrocytes on tissue culture polystyrene, for cell-based repair therapies, leads to …

Probing the Nanonewton Mitotic Cell Deformation Force by Ion-Resonance-Enhanced Photonics Force Microscopy

X Di, D Wang, X Shan, L Ding, Z Zhong, C Chen… - Nano Letters, 2024 - ACS Publications
Mechanical forces are essential for regulating dynamic changes in cellular activities. A
comprehensive understanding of these forces is imperative for unraveling fundamental …

Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia

Z Mann, F Lim, S Verma, BN Nanavati… - … Biology of the Cell, 2023 - pmc.ncbi.nlm.nih.gov
Apical extrusion is a tissue-intrinsic process that allows epithelia to eliminate unfit or surplus
cells. This is exemplified by the early extrusion of apoptotic cells, which is critical to maintain …