[HTML][HTML] Mitochondrial dysfunction, oxidative stress, and neuroinflammation: Intertwined roads to neurodegeneration

A Picca, R Calvani, HJ Coelho-Junior, F Landi… - Antioxidants, 2020 - mdpi.com
Oxidative stress develops as a response to injury and reflects a breach in the cell's
antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

[HTML][HTML] Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)

NA Singh, AKA Mandal, ZA Khan - Nutrition journal, 2015 - Springer
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease
(PD) enforce an overwhelming social and economic burden on society. They are primarily …

[HTML][HTML] The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

[PDF][PDF] Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts

PM Kidd - Altern Med Rev, 2009 - researchgate.net
Plant-derived polyphenols are increasingly receiving attention as dietary supplements for
the homeostatic management of inflammation, to support detoxification, and for anticancer …

Berry flavonoids and phenolics: bioavailability and evidence of protective effects

D Del Rio, G Borges, A Crozier - British journal of nutrition, 2010 - cambridge.org
Berries contain vitamin C and are also a rich source of phytochemicals, especially
anthocyanins which occur along with other classes of phenolic compounds, including …

Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration

BA Sutherland, RMA Rahman, I Appleton - The Journal of nutritional …, 2006 - Elsevier
Catechins are dietary polyphenolic compounds associated with a wide variety of beneficial
health effects in vitro, in vivo and clinically. These therapeutic properties have long been …

Multifunctional activities of green tea catechins in neuroprotection

SA Mandel, Y Avramovich-Tirosh, L Reznichenko… - Neurosignals, 2005 - karger.com
Many lines of evidence suggest that oxidative stress resulting in reactive oxygen species
(ROS) generation and inflammation play a pivotal role in the age-associated cognitive …

Unveiling the intricate supramolecular chemistry of γ-cyclodextrin-epigallocatechin gallate inclusion complexes

P Kumar, VK Bhardwaj, R Purohit - Industrial & Engineering …, 2024 - ACS Publications
Green tea's main polyphenol, epigallocatechin-gallate (EgCg), garners attention for diverse
health-promoting properties. Due to the limited bioavailability of EgCg, drug formulation …

Synthetic and natural iron chelators: therapeutic potential and clinical use

HC Hatcher, RN Singh, FM Torti… - Future medicinal …, 2009 - Taylor & Francis
Iron-chelation therapy has its origins in the treatment of iron-overload syndromes. For many
years, the standard for this purpose has been deferoxamine. Recently, considerable …