Patients with severe uncontrolled asthma have disproportionally high morbidity and
healthcare utilization as compared with their peers with well-controlled disease. Although …

Biodiversity hypothesis states that contact with natural environments enriches the human
microbiome, promotes immune balance and protects from allergy and inflammatory …

Recent developments in therapeutic strategies have provided alternatives to corticosteroids
as the cornerstone treatment for managing airway inflammation in asthma. The past two …

Eosinophils are an enigmatic white blood cell, whose immune functions are still under
intense investigation. Classically, the eosinophil was considered to fulfill a protective role …

Immune modulation is one of the most effective approaches in the therapy of complex
diseases, including public health emergency. However, most immune therapeutics such as …

Age is a major risk factor for chronic respiratory diseases such as idiopathic pulmonary
fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and certain phenotypes of …

A major burden of severe asthma is the future risk of adverse health outcomes. Patients with
severe asthma are prone to serious exacerbation and deterioration of lung function and may …

Advances in the understanding that severe asthma is a complex and heterogeneous
disease and in the knowledge of the pathophysiology of asthma, with the identification of …

Asthma is a multifactorial disorder characterized by the airway chronic inflammation, hyper-
responsiveness (AHR), remodeling, and reversible obstruction. Although asthma is known …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 pandemic
has taken away the lives of many people (> 4 million per WHO) around the world as of July …