Is there etiologic heterogeneity between subtypes of childhood acute lymphoblastic leukemia? A review of variation in risk by subtype
Although substantial advances in the identification of cytogenomic subtypes of childhood
acute lymphoblastic leukemia (ALL) have been made in recent decades, epidemiologic …
acute lymphoblastic leukemia (ALL) have been made in recent decades, epidemiologic …
Genetic susceptibility in childhood acute lymphoblastic leukemia
A Gutierrez-Camino, I Martin-Guerrero, A García-Orad - Medical Oncology, 2017 - Springer
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and a
leading cause of death due to disease in children. The genetic basis of ALL susceptibility …
leading cause of death due to disease in children. The genetic basis of ALL susceptibility …
ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis
WZ Leong, SH Tan, PCT Ngoc, S Amanda… - Genes & …, 2017 - genesdev.cshlp.org
The oncogenic transcription factor TAL1/SCL induces an aberrant transcriptional program in
T-cell acute lymphoblastic leukemia (T-ALL) cells. However, the critical factors that are …
T-cell acute lymphoblastic leukemia (T-ALL) cells. However, the critical factors that are …
The role of ARID5B in acute lymphoblastic leukemia and beyond
Acute lymphoblastic leukemia (ALL) is the most common malignancy in children with distinct
characteristics among different subtypes. Although the etiology of ALL has not been fully …
characteristics among different subtypes. Although the etiology of ALL has not been fully …
Contribution of polymorphisms in IKZF1 gene to childhood acute leukemia: a meta-analysis of 33 case-control studies
Y Dai, L Tang, J Healy, D Sinnett - PloS one, 2014 - journals.plos.org
Objective Two common polymorphisms in the IKZF1 gene (rs4132601 and rs11978267
variants) have been reported to be associated with childhood acute leukemia (AL) risk …
variants) have been reported to be associated with childhood acute leukemia (AL) risk …
IKZF1 Gene in Childhood B-cell Precursor Acute Lymphoblastic Leukemia: Interplay between Genetic Susceptibility and Somatic Abnormalities
SNPs in IKZF1 are associated with inherited susceptibility to B-cell precursor acute
lymphoblastic leukemia (BCP-ALL). Besides, somatic copy number abnormalities (CNA) in …
lymphoblastic leukemia (BCP-ALL). Besides, somatic copy number abnormalities (CNA) in …
Associations between AT-rich interactive domain 5B gene polymorphisms and risk of childhood acute lymphoblastic leukemia: a meta-analysis
H Zeng, XB Wang, NH Cui, S Nam… - Asian Pacific Journal …, 2014 - koreascience.kr
Previous genome-wide association studies (GWAS) have implicated several single
nucleotide polymorphisms (SNPs) in the AT-rich interactive domain 5B (ARID5B) gene with …
nucleotide polymorphisms (SNPs) in the AT-rich interactive domain 5B (ARID5B) gene with …
Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child …
Childhood acute lymphoblastic leukemia (ALL) peaks around age 2–4, and in utero genetic
epigenetic mother-fetus crosstalk might tune ALL onset during childhood life. Folate genes …
epigenetic mother-fetus crosstalk might tune ALL onset during childhood life. Folate genes …
Association between CEBPE variant and childhood acute leukemia risk: evidence from a meta-analysis of 22 studies
J Sun, J Zheng, L Tang, J Healy, D Sinnett, Y Dai - PloS one, 2015 - journals.plos.org
The CCAAT/enhancer binding proteins (CEBPs) have been involved in the etiology of acute
leukemia (AL) and investigated in numerous genetic association studies, however, the …
leukemia (AL) and investigated in numerous genetic association studies, however, the …
[HTML][HTML] Heritable genetic background alters survival and phenotype of Mll-AF9-induced leukemias
The MLL-AF9 fusion protein occurring as a result of t (9; 11) translocation gives rise to
pediatric and adult acute leukemias of distinct lineages, including acute lymphoblastic …
pediatric and adult acute leukemias of distinct lineages, including acute lymphoblastic …