Progress has been made in the prevention and treatment of community-acquired bacterial
meningitis during the past three decades but the burden of the disease remains high …

The blood–brain barrier (BBB) has a pivotal role in maintaining brain homeostasis. It
robustly protects the brain parenchyma against the invasion of irrelevant substances, which …

The blood–brain barrier (BBB) is a critical component of the central nervous system that
protects neurons and other cells of the brain parenchyma from potentially harmful …

Coxsackievirus B3 (CVB3) is a significant human pathogen that is commonly found
worldwide. CVB3 among other enteroviruses, are the leading causes of aseptic meningo …

Microbe-induced meningoencephalitis/meningitis is a life-threatening infection of the central
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …

Bacterial meningitis is defined as serious inflammation of the central nervous system (CNS)
in which bacteria infect the blood–brain barrier (BBB), a network of highly specialized brain …

A new cell line was established from the brain of a cultured fish, tilapia (Oreochromis
niloticus), designated as TA‐02 (Tilapia Astrocyte clone 02 cell line). The TA‐02 cells are …

Infections of the central nervous system (CNS) are still a major cause of morbidity and
mortality worldwide. Traversal of the barriers protecting the brain by pathogens is a …

The blood–brain barrier (BBB) is a continuous endothelial barrier that is supported by
pericytes and astrocytes and regulates the passage of solutes between the bloodstream and …

Invasion of brain endothelial cells (BECs) is central to the pathogenicity of Neisseria
meningitidis infection. Here, we established a key role for the bioactive sphingolipid …