Water as an active constituent in cell biology

P Ball - Chemical reviews, 2008 - ACS Publications
When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

Peptoids and polypeptoids at the frontier of supra-and macromolecular engineering

N Gangloff, J Ulbricht, T Lorson, H Schlaad… - Chemical …, 2016 - ACS Publications
In most general terms, polymers and their supramolecular assemblies have been defining
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …

Peptoid polymers: a highly designable bioinspired material

J Sun, RN Zuckermann - ACS nano, 2013 - ACS Publications
Bioinspired polymeric materials are attracting increasing attention due to significant
advantages over their natural counterparts: the ability to precisely tune their structures over a …

Applications of discrete synthetic macromolecules in life and materials science: recent and future trends

R Aksakal, C Mertens, M Soete, N Badi… - Advanced …, 2021 - Wiley Online Library
In the last decade, the field of sequence‐defined polymers and related ultraprecise,
monodisperse synthetic macromolecules has grown exponentially. In the early stage, mainly …

Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens

JE Nielsen, MA Alford, DBY Yung… - ACS infectious …, 2022 - ACS Publications
Antimicrobial peptides (AMPs) are promising pharmaceutical candidates for the prevention
and treatment of infections caused by multidrug-resistant ESKAPE pathogens, which are …

Microwave heating in solid-phase peptide synthesis

SL Pedersen, AP Tofteng, L Malik… - Chemical Society …, 2012 - pubs.rsc.org
The highly refined organic chemistry in solid-phase synthesis has made it the method of
choice not only to assemble peptides but also small proteins–mainly on a laboratory scale …

Sequence programmable peptoid polymers for diverse materials applications

AS Knight, EY Zhou, MB Francis… - Advanced …, 2015 - Wiley Online Library
Polymer sequence programmability is required for the diverse structures and complex
properties that are achieved by native biological polymers, but efforts towards controlling the …

Structure–function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function

SA Fowler, HE Blackwell - Organic & biomolecular chemistry, 2009 - pubs.rsc.org
Oligomers of N-substituted glycine, or peptoids, are versatile tools to probe biological
processes and hold promise as therapeutic agents. An underlying theme in the majority of …

Peptoid origins

RN Zuckermann - Peptide Science, 2011 - Wiley Online Library
Peptoid oligomers were initially developed as part of a larger basic research effort to
accelerate the drug‐discovery process in the biotech/biopharma industry. Their ease of …

Cyclic peptoids

SBY Shin, B Yoo, LJ Todaro… - Journal of the American …, 2007 - ACS Publications
Foldamers are an intriguing family of biomimetic oligomers that exhibit a propensity to adopt
stable secondary structures. N-Substituted glycine oligomers, or “peptoids”, are a …