C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic support to axons, is conventionally thought of as a static structure that is set early in …
D Keller, C Erö, H Markram - Frontiers in neuroanatomy, 2018 - frontiersin.org
The mouse brain is the most extensively studied brain of all species. We performed an exhaustive review of the literature to establish our current state of knowledge on cell …
M Monje - Annual review of neuroscience, 2018 - annualreviews.org
Structural plasticity in the myelinated infrastructure of the nervous system has come to light. Although an innate program of myelin development proceeds independent of nervous …
HJ Luhmann, A Sinning, JW Yang… - Frontiers in neural …, 2016 - frontiersin.org
Neuronal activity has been shown to be essential for the proper formation of neuronal circuits, affecting developmental processes like neurogenesis, migration, programmed cell …
KD Micheva, D Wolman, BD Mensh, E Pax… - elife, 2016 - elifesciences.org
Myelin is best known for its role in increasing the conduction velocity and metabolic efficiency of long-range excitatory axons. Accordingly, the myelin observed in neocortical …
KK Bercury, WB Macklin - Developmental cell, 2015 - cell.com
Vertebrate myelination is an evolutionary advancement essential for motor, sensory, and higher-order cognitive function. CNS myelin, a multilamellar differentiation of the …
Conduction time is typically ignored in computational models of neural network function. Here we consider the effects of conduction delays on the synchrony of neuronal activity and …
AN Hughes, B Appel - Nature communications, 2019 - nature.com
Vesicular release from neurons promotes myelin sheath growth on axons. Oligodendrocytes express proteins that allow dendrites to respond to vesicular release at synapses …