The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent …

Calcium homeostasis plays an essential role in maintaining excitation–contraction coupling
(ECC) in cardiomyocytes, including calcium release, recapture, and storage. Disruption of …

Aggregation of α‐synuclein is a hallmark of Parkinson's disease and dementia with Lewy
bodies. We here investigate the relationship between cytosolic Ca2+ and α‐synuclein …

Background Stroke is a leading cause of long-term disability. All neuroprotectants targeting
excitotoxicity have failed to become stroke medications. In order to explore and identify new …

New Findings What is the topic of this review? This paper overviews the links between Ca2+
and Na+ signalling in various types of cells. What advances does it highlight? This paper …

Background Salinity, as one of the main abiotic stresses, critically threatens growth and
fertility of main food crops including rice in the world. To get insight into the molecular …

Hydrogen/Deuterium eXchange Mass Spectrometry (HDX-MS) is a rapidly evolving
technique for analyzing structural features and dynamic properties of proteins. It may stand …

Mechanosensitive ion channels are widely expressed in the cardiovascular system. They
translate mechanical forces including shear stress and stretch into biological signals. The …

Ca 2+ homeostasis is essential for cell function and survival. As such, the cytosolic Ca 2+
concentration is tightly controlled by a wide number of specialized Ca 2+ handling proteins …

Owing to the excellent antibacterial and antiviral activity, silver nanoparticles have a
widespread use in the food and pharmaceutical industries. With the increase in the …