Giant cell arteritis is the most common form of large vessel vasculitis and preferentially
involves large and medium-sized arteries in patients over the age of 50. Aggressive wall …

Giant cell arteritis is the principal form of systemic vasculitis affecting people over 50. Large-
vessel involvement, termed large vessel giant cell arteritis, mainly affects the aorta and its …

Objective To identify the key coding genes underlying the biomarkers and pathways
associated with giant cell arteritis (GCA), we performed an in situ spatial profiling of …

Background Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) are overlapping
inflammatory diseases. Antigen-presenting cells (APCs), including monocytes and dendritic …

BACKGROUND: Kawasaki disease (KD) and multisystem inflammatory syndrome in
children (MIS-C) share similar clinical manifestations, including cardiovascular …

Vascular smooth muscle cells (VSMCs) have been shown to play a role in the pathogenesis
of giant cell arteritis (GCA) through their capacity to produce chemokines recruiting T cells …

Background Giant cell arteritis (GCA) is a primary large-vessel vasculitis (LVV) of unknown
origin. Its management is a challenge due to the late onset of disease symptoms and …

Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are two types of primary large vessel
vasculitis (LVV). LVV is an intractable, rare disease with a high relapse rate. Disease …

Introduction Giant cell arteritis (GCA) is a vasculitis of the medium-and large-sized arteries.
Interferon type I (IFN-I) is increasingly recognized as a key player in autoimmune diseases …