The cortical motor areas and the emergence of motor skills: a neuroanatomical perspective

PL Strick, RP Dum, JA Rathelot - Annual Review of …, 2021 - annualreviews.org
What changes in neural architecture account for the emergence and expansion of dexterity
in primates? Dexterity, or skill in performing motor tasks, depends on the ability to generate …

Sex differences in the neurochemistry of frontal cortex: Impact of early life stress

CJ Perry, EJ Campbell, KD Drummond… - Journal of …, 2021 - Wiley Online Library
Traumatic events during early life have been linked with later life psychopathology. To
understand this risk factor, researchers have studied the effects of prenatal and postnatal …

[HTML][HTML] Context-dependent decision making in a premotor circuit

Z Wu, A Litwin-Kumar, P Shamash, A Taylor, R Axel… - Neuron, 2020 - cell.com
Cognitive capacities afford contingent associations between sensory information and
behavioral responses. We studied this problem using an olfactory delayed match to sample …

The rat frontal orienting field dynamically encodes value for economic decisions under risk

C Bao, X Zhu, J Mōller-Mara, J Li, S Dubroqua… - Nature …, 2023 - nature.com
Frontal and parietal cortex are implicated in economic decision-making, but their causal
roles are untested. Here we silenced the frontal orienting field (FOF) and posterior parietal …

Parallel and serial sensory processing in developing primary somatosensory and motor cortex

LJ Gómez, JC Dooley, G Sokoloff… - Journal of …, 2021 - Soc Neuroscience
It is generally supposed that primary motor cortex (M1) receives somatosensory input
predominantly via primary somatosensory cortex (S1). However, a growing body of evidence …

Movements during sleep reveal the developmental emergence of a cerebellar-dependent internal model in motor thalamus

JC Dooley, G Sokoloff, MS Blumberg - Current Biology, 2021 - cell.com
With our eyes closed, we can track a limb's moment-to-moment location in space. If this
capacity relied solely on sensory feedback from the limb, we would always be a step behind …

Multimodal measures of spontaneous brain activity reveal both common and divergent patterns of cortical functional organization

H Vafaii, F Mandino, G Desrosiers-Grégoire… - Nature …, 2024 - nature.com
Large-scale functional networks have been characterized in both rodent and human brains,
typically by analyzing fMRI-BOLD signals. However, the relationship between fMRI-BOLD …

Mouse frontal cortex mediates additive multisensory decisions

P Coen, TPH Sit, MJ Wells, M Carandini, KD Harris - Neuron, 2023 - cell.com
The brain can combine auditory and visual information to localize objects. However, the
cortical substrates underlying audiovisual integration remain uncertain. Here, we show that …

Motor cortex can directly drive the globus pallidus neurons in a projection neuron type-dependent manner in the rat

F Karube, S Takahashi, K Kobayashi, F Fujiyama - Elife, 2019 - elifesciences.org
The basal ganglia are critical for the control of motor behaviors and for reinforcement
learning. Here, we demonstrate in rats that primary and secondary motor areas (M1 and M2) …

[HTML][HTML] Large-scale all-optical dissection of motor cortex connectivity shows a segregated organization of mouse forelimb representations

F Resta, E Montagni, G de Vito, A Scaglione… - Cell Reports, 2022 - cell.com
In rodent motor cortex, the rostral forelimb area (RFA) and the caudal forelimb area (CFA)
are major actors in orchestrating the control of complex forelimb movements. However, their …