Abstract Over 30 years ago Professor David Barker first proposed the theory that events in
early life could explain an individual's risk of non‐communicable disease in later life: the …

Perinatal asphyxia is caused by lack of oxygen delivery (hypoxia) to end organs due to an
hypoxemic or ischemic insult occurring in temporal proximity to labor (peripartum) or delivery …

Background Severe early-onset fetal growth restriction can lead to a range of adverse
outcomes including fetal or neonatal death, neurodisability, and lifelong risks to the health of …

Sildenafil is a new approach to treat fetal growth restriction (FGR) and preeclampsia. We
performed a systematic meta-analysis to evaluate effects of sildenafil. Our search identified …

Background: To determine whether the phosphodiesterase type 5 inhibitor, Sildenafil citrate,
affects uteroplacental perfusion. Materials and Methods: Based on a randomized double …

Normal pregnancy leads to profound maternal hemodynamic changes, including increased
blood volume and vasodilatation. Several vasodilator mediators are implicated, including …

Background Severe, early-onset fetal growth restriction due to placental insufficiency is
associated with a high risk of perinatal mortality and morbidity with long-lasting sequelae …

Please cite this paper as: Herraiz S, Pellicer B., Serra V, Cauli O, Cortijo J, Felipo V, Pellicer
A. Sildenafil citrate improves perinatal outcome in fetuses from pre‐eclamptic rats. BJOG …

The aim of this review was to elaborate a conceptual framework of the most important
aspects of the main biochemical processes of synthesis and breakdown of energy …

The objective of this review is to integrate clinical findings and laboratory analyses in such a
way to improve the welfare of newborn piglets and achieve better prognoses of neonatal …