Insulin sensitivity: modulation by nutrients and inflammation

S Schenk, M Saberi, JM Olefsky - The Journal of clinical …, 2008 - Am Soc Clin Investig
Insulin resistance is a major metabolic feature of obesity and is a key factor in the etiology of
a number of diseases, including type 2 diabetes. In this review, we discuss potential …

Hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery

JP Thaler, DE Cummings - Endocrinology, 2009 - academic.oup.com
Bariatric surgery is the most effective available treatment for obesity. The most frequently
performed operation, Roux-en-Y gastric bypass (RYGB), causes profound weight loss and …

The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes

F Rubino, A Forgione, DE Cummings, M Vix… - Annals of …, 2006 - journals.lww.com
Methods: Goto-Kakizaki (GK) type 2 diabetic rats underwent duodenal-jejunal bypass (DJB),
a stomach-preserving RYGB that excludes the proximal intestine, or a gastrojejunostomy …

Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial

WJ Lee, K Chong, KH Ser, YC Lee, SC Chen… - Archives of …, 2011 - jamanetwork.com
Objectives To determine the efficacies of 2 weight-reducing operations on diabetic control
and the role of duodenum exclusion. Design Double-blind randomized controlled trial …

Sleeve gastrectomy for morbid obesity

AA Gumbs, M Gagner, G Dakin, A Pomp - Obesity surgery, 2007 - Springer
The rising prevalence of morbid obesity and the increased incidence of super-obese
patients (BMI> 50 kg/m2) seeking surgical treatments has led to the search for surgical …

The importance of caloric restriction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery

JM Isbell, RA Tamboli, EN Hansen, J Saliba… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Many of the metabolic benefits of Roux-en-Y gastric bypass (RYGB) occur
before weight loss. In this study we investigated the influence of caloric restriction on the …

Results of laparoscopic sleeve gastrectomy (LSG) at 1 year in morbidly obese Korean patients

S Moon Han, WW Kim, JH Oh - Obesity surgery, 2005 - Springer
Background: In Asia, the type and main cause of obesity is different than in western society.
Therefore, the treatment plan should be differentiated, and the surgery for morbid obesity …

Circadian rhythms in diet-induced obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
The biological clocks of the circadian timing system coordinate cellular and physiological
processes and synchronizes these with daily cycles, feeding patterns also regulates …

Bile acids and bariatric surgery

VL Albaugh, B Banan, H Ajouz, NN Abumrad… - Molecular aspects of …, 2017 - Elsevier
Bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB) and vertical sleeve
gastrectomy (VSG), are the most effective and durable treatments for morbid obesity and …

Type 2 diabetes and viral infection; cause and effect of disease

TT Wensveen, D Gašparini, D Rahelić… - Diabetes research and …, 2021 - Elsevier
The recent pandemic of COVID-19 has made abundantly clear that Type 2 diabetes (T2D)
increases the risk of more frequent and more severe viral infections. At the same time, pro …