Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals
infected with HIV-1. It has long been known that HIV-1 infection alters the course of M …

The risk of progression from exposure to the tuberculosis bacilli to the development of active
disease is a two‐stage process governed by both exogenous and endogenous risk factors …

Tuberculosis (TB) and HIV co-infections place an immense burden on health care systems
and pose particular diagnostic and therapeutic challenges. Infection with HIV is the most …

Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency
syndrome (HIV/AIDS) constitute the main burden of infectious disease in resource-limited …

SUMMARY A syndemic is defined as the convergence of two or more diseases that act
synergistically to magnify the burden of disease. The intersection and syndemic interaction …

Knowledge of the molecular genetic basis of resistance to antituberculous agents has
advanced rapidly since we reviewed this topic 3 years ago. Virtually all isolates resistant to …

Improved treatments are needed for nearly all forms of Mycobacterium tuberculosis infection.
Adjunctive host-directed therapies have the potential to shorten tuberculosis treatment …

The peritoneum is one of the most common extrapulmonary sites of tuberculous infection.
Peritoneal tuberculosis remains a significant problem in parts of the world where …

HIV/AIDS pandemic has caused a resurgence of TB, resulting in increased morbidity and
mortality worldwide. HIV and Mycobacterium tuberculosis have a synergistic interaction; …

Mycobacterium tuberculosis can persist within the human host for years without causing
disease, in a syndrome known as latent tuberculosis (TB). As one-third of the world …