The neuropathology of chronic traumatic encephalopathy

AC McKee, TD Stein, PT Kiernan, VE Alvarez - Brain pathology, 2015 - Wiley Online Library
Repetitive brain trauma is associated with a progressive neurological deterioration, now
termed as chronic traumatic encephalopathy (CTE). Most instances of CTE occur in …

Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males

DH Daneshvar, ES Nair, ZH Baucom, A Rasch… - Nature …, 2023 - nature.com
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with
repetitive head impacts (RHI), but the components of RHI exposure underlying this …

Concussion under-reporting and pressure from coaches, teammates, fans, and parents

E Kroshus, B Garnett, M Hawrilenko, CM Baugh… - Social science & …, 2015 - Elsevier
Concussions from sport present a substantial public health burden given the number of
youth, adolescent and emerging adult athletes that participate in contact or collision sports …

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

CA Tagge, AM Fisher, OV Minaeva… - Brain, 2018 - academic.oup.com
The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …

Age of first exposure to football and later-life cognitive impairment in former NFL players

JM Stamm, AP Bourlas, CM Baugh, NG Fritts… - Neurology, 2015 - AAN Enterprises
Objective: To determine the relationship between exposure to repeated head impacts
through tackle football prior to age 12, during a key period of brain development, and later …

Diffusion tensor imaging (DTI) findings in adult civilian, military, and sport-related mild traumatic brain injury (mTBI): a systematic critical review

BM Asken, ST DeKosky, JR Clugston, MS Jaffee… - Brain imaging and …, 2018 - Springer
This review seeks to summarize diffusion tensor imaging (DTI) studies that have evaluated
structural changes attributed to the mechanisms of mild traumatic brain injury (mTBI) in adult …

Age of first exposure to American football and long-term neuropsychiatric and cognitive outcomes

ML Alosco, AB Kasimis, JM Stamm, AS Chua… - Translational …, 2017 - nature.com
Previous research suggests that age of first exposure (AFE) to football before age 12 may
have long-term clinical implications; however, this relationship has only been examined in …

[HTML][HTML] The effect of repetitive subconcussive collisions on brain integrity in collegiate football players over a single football season: a multi-modal neuroimaging …

SM Slobounov, A Walter, HC Breiter, DC Zhu, X Bai… - Neuroimage …, 2017 - Elsevier
The cumulative effect of repetitive subconcussive collisions on the structural and functional
integrity of the brain remains largely unknown. Athletes in collision sports, like football …

The immunological response to traumatic brain injury

EJ Needham, A Helmy, ER Zanier, JL Jones… - Journal of …, 2019 - Elsevier
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the
developed world. The accuracy of early outcome-prediction remains poor even when all …

Imaging of glial cell activation and white matter integrity in brains of active and recently retired national football league players

JM Coughlin, Y Wang, I Minn, N Bienko… - JAMA …, 2017 - jamanetwork.com
Importance Microglia, the resident immune cells of the central nervous system, play an
important role in the brain's response to injury and neurodegenerative processes. It has …