Leishmaniasis is a vector-borne neglected tropical disease that affects more than 700,000
people annually. Leishmania parasites cause the disease, and different species trigger a …

Leishmaniases are vector-borne diseases of serious public health importance. During a
sand fly blood meal, Leishmania parasites are deposited in the host dermis where …

The C-type lectin receptor–Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective
antifungal immunity within the central nervous system (CNS), as human deficiency in …

Leishmaniasis is endemic to the tropical and subtropical regions of the world and is
transmitted by the bite of an infected sand fly. The multifaceted interactions between …

Leishmania (L.) are obligate intracellular protozoan parasites that cause the leishmaniases,
a spectrum of neglected infectious vector-borne diseases with a broad range of clinical …

Neutrophil extracellular traps (NETs) are DNA fibers associated with histones, enzymes from
neutrophil granules and anti-microbial peptides. NETs are released in a process …

Neutrophils are the most abundant leukocytes in human blood. Upon microbial infection,
they are massively and rapidly recruited from the circulation to sites of infection where they …

Neutrophils rapidly infiltrate sites of infection and possess several microbicidal strategies,
such as neutrophil extracellular traps release and phagocytosis. Enhanced neutrophil …

Leishmaniases are neglected diseases, caused by intracellular protozoan parasites of the
Leishmania (L.) genus. Although the principal host cells of the parasites are macrophages …

The recognition of invading pathogens by the innate immune system is essential for host
protection against human parasites and the initiation of an effective adaptive immune …