Treatment of acute lymphoblastic leukemia

CH Pui, WE Evans - New England Journal of Medicine, 2006 - Mass Medical Soc
Although the overall cure rate of acute lymphoblastic leukemia (ALL) in children is about 80
percent, affected adults fare less well. This review considers recent advances in the …

Acute lymphoblastic leukaemia

CH Pui, LL Robison, AT Look - The Lancet, 2008 - thelancet.com
Acute lymphoblastic leukaemia, a malignant disorder of lymphoid progenitor cells, affects
both children and adults, with peak prevalence between the ages of 2 and 5 years. Steady …

[PDF][PDF] Using deep learning to enhance cancer diagnosis and classification

R Fakoor, F Ladhak, A Nazi… - Proceedings of the …, 2013 - admis.tongji.edu.cn
Using automated computer tools and in particular machine learning to facilitate and
enhance medical analysis and diagnosis is a promising and important area. In this paper …

Acute lymphoblastic leukemia

CH Pui, MV Relling, JR Downing - New England Journal of …, 2004 - Mass Medical Soc
Acute Lymphoblastic Leukemia | New England Journal of Medicine Skip to main content Access
provided by Charite - Universitaetsmedizin Berlin The New England Journal of Medicine …

Coexpression analysis of human genes across many microarray data sets

HK Lee, AK Hsu, J Sajdak, J Qin, P Pavlidis - Genome research, 2004 - genome.cshlp.org
We present a large-scale analysis of mRNA coexpression based on 60 large human data
sets containing a total of 3924 microarrays. We sought pairs of genes that were reliably …

Acute lymphoblastic leukemia

CH Pui, WE Evans - New England Journal of Medicine, 1998 - Mass Medical Soc
Acute lymphoblastic leukemia (ALL) is diagnosed in 3000 to 4000 persons in the United
States each year; two thirds of them are children. 1, 2 The current rate of cure of nearly 80 …

Moving towards individualized medicine with pharmacogenomics

WE Evans, MV Relling - Nature, 2004 - nature.com
Individuals respond differently to drugs and sometimes the effects are unpredictable.
Differences in DNA that alter the expression or function of proteins that are targeted by drugs …

Assessment of herbal medicinal products: challenges, and opportunities to increase the knowledge base for safety assessment

SA Jordan, DG Cunningham, RJ Marles - Toxicology and applied …, 2010 - Elsevier
Although herbal medicinal products (HMP) have been perceived by the public as relatively
low risk, there has been more recognition of the potential risks associated with this type of …

[HTML][HTML] A survey of neural network-based cancer prediction models from microarray data

M Daoud, M Mayo - Artificial intelligence in medicine, 2019 - Elsevier
Neural networks are powerful tools used widely for building cancer prediction models from
microarray data. We review the most recently proposed models to highlight the roles of …

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

A Holleman, MH Cheok, ML den Boer… - … England Journal of …, 2004 - Mass Medical Soc
Background Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in
approximately 80 percent of patients. However, the cause of treatment failure in the …