Background Autism spectrum disorder (ASD) is often accompanied by intellectual disability
(ID). Despite extensive studies, however, the genetic basis for this comorbidity is still not …

A hallmark of fetal alcohol spectrum disorders (FASD) is neurobehavioral deficits that still do
not have effective treatment. Here, we present that reduction of Apolipoprotein E (APOE) is …

Schizophrenia is a neurodevelopmental disorder whose etiopathogenesis includes changes
in cellular as well as extracellular structures. Perineuronal nets (PNNs) associated with …

Background Posttraumatic stress disorder (PTSD), a psychiatric disorder caused by stressful
events, is characterized by long-lasting fear memory. The nucleus accumbens shell (NAcS) …

The usage (abuse) of Datura metel is becoming increasingly worrisome among the Nigerian
populace especially among the youth considering its side effects such as hallucination. This …

A spontaneous mutation of the disrupted in schizophrenia 1 (Disc1) gene is carried by the
129S inbred mouse strain. Truncated DISC1 protein in 129S mouse synapses impairs the …

Abstract Ca 2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a multifunctional
Ser/Thr kinase involved in several neuronal signaling pathways including synaptic plasticity …

Neurons are thought to detect salient patterns amidst noise in continuous information
streams, but their rapidity tends to be overlooked. Consequently, theoretical neuron models …

Methods: 30 male adult BALB/c mice were used for the study. The mice were randomly
divided into three groups of ten mice each with an intraperitoneal injection of 0.1 mL of 10 …

Angelman syndrome (AS) is a neurodevelopmental disorder caused by the loss of function
of the E3-ligase UBE3A. Despite multiple studies, AS pathophysiology is still obscure and …