Our understanding of the role of the parabrachial nucleus (PBN) has evolved as technology
has advanced, in part due to cell-specific studies and complex behavioral assays. This is …

The forebrain plays important roles in many critical functions, including the control of
breathing. We propose that the forebrain is important for ensuring that breathing matches …

Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy,
leading to reduced health‐related quality of life (HRQOL). Prospective outcome data on …

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in refractory
epilepsy patients. Accumulating evidence from recent human studies and animal models …

Mutations in the SCN1A gene can cause a variety of phenotypes, ranging from mild forms,
such as febrile seizures and generalized epilepsy with febrile seizures plus, to severe, such …

Dravet syndrome (DS) is a channelopathy, neurodevelopmental, epileptic encephalopathy
characterized by seizures, developmental delay, and cognitive impairment that includes …

Epilepsy is an umbrella term used to define a wide variety of seizure disorders and sudden
unexpected death in epilepsy (SUDEP) is the leading cause of death in epilepsy. Although …

Dravet syndrome (DS) is a debilitating infantile epileptic encephalopathy characterized by
seizures induced by high body temperature (hyperthermia), sudden unexpected death in …

Early-life seizures can be refractory to conventional antiseizure medications (ASMs) and can
also result in chronic epilepsy and long-term behavioral and cognitive deficits. Treatments …

Epilepsy has a high prevalence and can severely impair quality of life and increase the risk
of premature death. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of …