The changing opioid crisis: development, challenges and opportunities

ND Volkow, C Blanco - Molecular psychiatry, 2021 - nature.com
The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …

Moving naloxone over the counter is necessary but not sufficient

JC Messinger, L Beletsky, AS Kesselheim… - Annals of Internal …, 2023 - acpjournals.org
Naloxone is an opioid antagonist that is available in numerous formulations and can be
easily administered to avert death from opioid overdose. Amid a historic overdose crisis in …

[HTML][HTML] Trends in out-of-pocket costs for naloxone by drug brand and payer in the US, 2010-2018

ED Peet, D Powell, RL Pacula - JAMA Health Forum, 2022 - jamanetwork.com
Importance Improving access to naloxone is a critical component of the nation's strategy to
curb fatal overdoses in the opioid crisis. Standing or protocol orders, prescriptive authority …

Mobilizing pharmacists to address the opioid crisis: a joint opinion of the ambulatory care and adult medicine practice and research networks of the American College …

SA Coon, LG Hill, RW Hutchison… - Journal of the …, 2020 - Wiley Online Library
The opioid crisis represents one of the largest failures of our current health care system as it
continues to claim lives at an unprecedented rate and has caused a devastating range of …

Considering the potential benefits of over-the-counter naloxone

KE Evoy, LG Hill, CS Davis - Integrated Pharmacy Research and …, 2021 - Taylor & Francis
Since 1999, annual opioid-related overdose (ORO) mortality has increased more than six-
fold. In response to this crisis, the US Department of Health and Human Services outlined a …

Variation in initiation, engagement, and retention on medications for opioid use disorder based on health insurance plan design

JR Morgan, EK Quinn, CE Chaisson, E Ciemins… - Medical care, 2022 - journals.lww.com
Background: The association between cost-sharing and receipt of medication for opioid use
disorder (MOUD) is unknown. Methods: We constructed a cohort of 10,513 commercially …

Over the counter naloxone needed to save lives in the United States

CS Davis, D Carr - Preventive Medicine, 2020 - Elsevier
Abstract The United States continues to face a public health emergency of opioid-related
harm, the effects of which could be dramatically reduced through increased access to the …

Association Between Cost Sharing and Naloxone Prescription Dispensing

KP Chua, RM Conti, P Lagisetty, AS Bohnert, S He… - JAMA, 2024 - jamanetwork.com
Importance Increasing access to naloxone (an opioid antagonist that can reverse overdose)
could slow the US opioid epidemic. Prior studies suggest cost sharing may be a barrier to …

[HTML][HTML] Investigating the complexity of naloxone distribution: Which policies matter for pharmacies and potential recipients

R Smart, D Powell, RL Pacula, E Peet, R Abouk… - Journal of health …, 2024 - Elsevier
Despite efforts to expand naloxone access, opioid-related overdoses remain a significant
contributor to mortality. We study state efforts to expand naloxone distribution through …

Association of opioid overdose risk factors and naloxone prescribing in US adults

L Lin, CM Brummett, JF Waljee, MJ Englesbe… - Journal of General …, 2020 - Springer
Background Prescribing naloxone to patients is a key strategy to prevent opioid overdoses,
but little is known about the reach of naloxone prescribing. Objective Determine patient …