Abstract Three-dimensional (3D) printing enables the production of anatomically matched
and patient-specific devices and constructs with high tunability and complexity. It also allows …

Silk fibroin (SF) is a fibrous protein which is produced mainly by silkworms and spiders. Its
unique mechanical properties, tunable biodegradation rate and the ability to support the …

In the human body, almost all cells interact with extracellular matrices (ECMs), which have
tissue and organ-specific compositions and architectures. These ECMs not only function as …

The natural microenvironment of tumors is composed of extracellular matrix (ECM), blood
vasculature, and supporting stromal cells. The physical characteristics of ECM as well as the …

Introduction: Developing in vitro models for studying cell biology and cell physiology is of
great importance to the fields of biotechnology, cancer research, drug discovery, toxicity …

Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …

Building human tissues via 3D cell printing technology has received particular attention due
to its process flexibility and versatility. This technology enables the recapitulation of unique …

In vitro tissue/organ models are useful platforms that can facilitate systematic, repetitive, and
quantitative investigations of drugs/chemicals. The primary objective when developing …

The survival of engineered tissue constructs during the initial phase after their implantation
depends on the rapid development of an adequate vascularization. This, in turn, is a major …

Drug candidate and toxicity screening processes currently rely on results from early-stage in
vitro cell-based assays expected to faithfully represent essential aspects of in vivo …