Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy

DI Ellis, R Goodacre - Analyst, 2006 - pubs.rsc.org
The ability to diagnose the early onset of disease, rapidly, non-invasively and unequivocally
has multiple benefits. These include the early intervention of therapeutic strategies leading …

Metabolic fingerprinting as a diagnostic tool

DI Ellis, WB Dunn, JL Griffin, JW Allwood… - …, 2007 - Taylor & Francis
Within the framework of systems biology, functional analyses at all 'omic levels have seen an
intense level of activity during the first decade of the twenty-first century. These include …

Automated autofluorescence background subtraction algorithm for biomedical Raman spectroscopy

J Zhao, H Lui, DI McLean, H Zeng - Applied spectroscopy, 2007 - journals.sagepub.com
A significant advantage of Raman spectroscopy as a noninvasive optical technique is its
ability to detect subtle molecular or biochemical signatures within tissue. One of the major …

Measuring the effects of topical moisturizers on changes in stratum corneum thickness, water gradients and hydration in vivo

JM Crowther, A Sieg, P Blenkiron… - British journal of …, 2008 - academic.oup.com
Background Moisturizers are the most commonly used topically applied product for the
treatment of dry skin conditions. They affect many properties and functions of the stratum …

Applications of Raman spectroscopy in skin research—from skin physiology and diagnosis up to risk assessment and dermal drug delivery

L Franzen, M Windbergs - Advanced drug delivery reviews, 2015 - Elsevier
In the field of skin research, confocal Raman microscopy is an upcoming analytical
technique. Substantial technical progress in design and performance of the individual setup …

Effects of atmospheric relative humidity on Stratum Corneum structure at the molecular level: ex vivo Raman spectroscopy analysis

R Vyumvuhore, A Tfayli, H Duplan, A Delalleau… - Analyst, 2013 - pubs.rsc.org
Skin hydration plays an important role in the optimal physical properties and physiological
functions of the skin. Despite the advancements in the last decade, dry skin remains the …

Comparison of the stratum corneum thickness measured in vivo with confocal Raman spectroscopy and confocal reflectance microscopy

A Böhling, S Bielfeldt, A Himmelmann… - Skin Research and …, 2014 - Wiley Online Library
Background Thickness measurement of the outermost layer of the skin, the stratum corneum
(SC), is essential for in‐vivo measurement of the cutaneous bioavailability of topically …

Miniaturized 7-in-1 fiber-optic Raman probe

B Zhang, RE Gerald, J Huang - Optics Letters, 2022 - opg.optica.org
This Letter reports a miniature 7-in-1 fiber-optic Raman probe that eliminates the inelastic
background Raman signal from a long-fused silica fiber. Its foremost purpose is to enhance …

Integrated real‐time Raman system for clinical in vivo skin analysis

J Zhao, H Lui, DI McLean… - Skin Research and …, 2008 - Wiley Online Library
Background: Raman spectroscopy is a non‐invasive optical technique that can probe the
molecular structure and conformation of biochemical constituents. The probability of Raman …

Ex vivo diagnosis of lung cancer using a Raman miniprobe

ND Magee, JS Villaumie, ET Marple… - The Journal of …, 2009 - ACS Publications
Lung cancer is the most common cause of cancer death. The conventional method of
confirming the diagnosis is bronchoscopy, inspecting the airways of the patient with a fiber …