Despite decades of research related to hemolysis, the accuracy of prediction algorithms for
complex flows leaves much to be desired. Fundamental questions remain about how …

Experimental flow field characterization is a critical component of the assessment of the
hemolytic and thrombogenic potential of heart valve substitutes, thus it is important to identify …

In this study, we explore how blood-material interactions and hemodynamics are impacted
by rendering a clinical quality 25 mm St. Jude Medical Bileaflet mechanical heart valve …

Shear stress on blood cells and platelets transported in a turbulent flow dictates the fate and
biological activity of these cells. We present a theoretical link between energy dissipation in …

Turbulent blood flow in medical devices contributes to blood trauma, yet the exact
mechanism (s) have not been fully elucidated. Local turbulent stresses, viscous stresses …

Existing hemolysis algorithms are often constructed for laminar flows that expose red blood
cells (RBCs) to a constant rate of shear. It remains an open question whether such models …

Artificial heart valves may expose blood to flow conditions that lead to unnaturally high
stress and damage to blood cells as well as issues with thrombosis. The purpose of this …

Reynolds shear stress (RSS) has served as a metric for the effect of turbulence on
hemolysis. Forstrom (1969) and Sallam and Hwang (1984) determined the RSS threshold …

Hemolysis is a persistent issue with blood-contacting devices. Many experimental and
theoretical contributions over the last few decades have increased insight into the …

In hemodynamics, the inherent intermittency of two-phase cellular-level flow has received
little attention. Unsteadiness is reported and quantified for the first time in the literature using …