The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …

There is currently no consensus on the combined length of small bowel that should be
bypassed as biliopancreatic or alimentary limb for optimum results with Roux-en-Y gastric …

A high-output stoma (HOS) or fistula is when small bowel output causes water, sodium and
often magnesium depletion. This tends to occur when the output is> 1.5-2.0 L/24 hours …

The following position statement is issued by the American Society for Metabolic and
Bariatric Surgery in response to inquiries made to the society by patients, physicians, society …

Background Small bowel length (SBL) determines the caloric absorptive capacity. The aim
of this study was to evaluate SBL to identify patient-specific predictors and the …

Abstract Background One Anastomosis Gastric Bypass–Mini Gastric Bypass (OAGB-MGB) is
rapidly gaining popularity and is currently being performed by an increasing number of …

Background Despite numerous studies on the enteric nervous system (ENS), we lack
fundamental knowledge on neuronal densities or total neuron numbers in different species …

Background Obesity is associated with physiological changes that can affect drug
pharmacokinetics. Obese individuals are underrepresented in clinical trials, leading to a lack …

Organ-on-chip devices (OoCs) provide more nuanced insights into (patho) physiological
processes of the human body than static tissue models, and are currently the most promising …