Toward oral supplementation of diamine oxidase for the treatment of histamine intolerance
L Kettner, I Seitl, L Fischer - Nutrients, 2022 - mdpi.com
A new diamine oxidase (DAO-1) was discovered recently in the yeast Yarrowia lipolytica
PO1f and investigated for its histamine degradation capability under simulated intestinal …
PO1f and investigated for its histamine degradation capability under simulated intestinal …
Multi-phasic life-threatening anaphylaxis refractory to epinephrine managed by extracorporeal membrane oxygenation (ECMO): a case report
J Grafeneder, F Ettl, AM Warenits, N Buchtele… - Frontiers in …, 2022 - frontiersin.org
We present a case of a 52-year-old patient suffering from multi-phasic life-threatening
anaphylaxis refractory to epinephrine treatment. Extracorporeal membrane oxygenation …
anaphylaxis refractory to epinephrine treatment. Extracorporeal membrane oxygenation …
[HTML][HTML] Massive release of TH2 cytokines induced a cytokine storm during a severe mast cell activation event in a patient with indolent systemic mastocytosis
T Boehm, R Ristl, J Mühlbacher, P Valent… - Journal of Allergy and …, 2022 - Elsevier
Background In subjects with systemic mastocytosis, the number of mast cells is elevated
many fold. These patients frequently experience unpredictable and recurrent life-threatening …
many fold. These patients frequently experience unpredictable and recurrent life-threatening …
Diamine oxidase knockout mice are not hypersensitive to orally or subcutaneously administered histamine
M Karer, M Rager-Resch, T Haider, K Petroczi… - Inflammation …, 2022 - Springer
Objective To evaluate the contribution of endogenous diamine oxidase (DAO) in the
inactivation of exogenous histamine, to find a mouse strain with increased histamine …
inactivation of exogenous histamine, to find a mouse strain with increased histamine …
Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs
M Weiss-Tessbach, B Reiter, E Gludovacz… - Inflammation …, 2023 - Springer
Objective To test whether recombinant human diamine oxidase (rhDAO) with a mutated
heparin-binding motif (mHBM), which shows an increased alpha-distribution half-life …
heparin-binding motif (mHBM), which shows an increased alpha-distribution half-life …
Glycosylation site Asn168 is important for slow in vivo clearance of recombinant human diamine oxidase heparin-binding motif mutants
E Gludovacz, M Resch, K Schuetzenberger… - …, 2022 - academic.oup.com
Elevated plasma and tissues histamine concentrations can cause severe symptoms in mast
cell activation syndrome, mastocytosis or anaphylaxis. Endogenous and recombinant …
cell activation syndrome, mastocytosis or anaphylaxis. Endogenous and recombinant …
[PDF][PDF] Central Role of Mast Cells in Mastocytosis, Hereditary α-Tryptasemia, Mast Cell Activation Syndrome, Urticaria, and Angioedema
M Rudenko, L Allergy - Allergy & Immunology, 2022 - emjreviews.com
Mast cells are the central cells in the pathogenesis of many conditions that are associated
with mediator release. New information is emerging about the role of mast cells in a number …
with mediator release. New information is emerging about the role of mast cells in a number …