Functional properties of human muscle spindles

VG Macefield, TP Knellwolf - Journal of neurophysiology, 2018 - journals.physiology.org
Muscle spindles are ubiquitous encapsulated mechanoreceptors found in most mammalian
muscles. There are two types of endings, primary and secondary, and both are sensitive to …

Lower motor neuron dysfunction in ALS

M de Carvalho, M Swash - Clinical Neurophysiology, 2016 - Elsevier
In the motor system there is a complex interplay between cortical structures and spinal cord
lower motor neurons (LMN). In this system both inhibitory and excitatory neurons have …

A neuronal least-action principle for real-time learning in cortical circuits

W Senn, D Dold, AF Kungl, B Ellenberger, J Jordan… - ELife, 2024 - elifesciences.org
One of the most fundamental laws of physics is the principle of least action. Motivated by its
predictive power, we introduce a neuronal least-action principle for cortical processing of …

[HTML][HTML] Next-generation prosthetic hand: from biomimetic to biorealistic

N Lan, M Hao, CM Niu, H Cui, Y Wang, T Zhang… - Research, 2021 - spj.science.org
Integrating a prosthetic hand to amputees with seamless neural compatibility presents a
grand challenge to neuroscientists and neural engineers for more than half century …

Linking cortex and contraction—Integrating models along the corticomuscular pathway

L Haggie, L Schmid, O Röhrle, T Besier… - Frontiers in …, 2023 - frontiersin.org
Computational models of the neuromusculoskeletal system provide a deterministic
approach to investigate input-output relationships in the human motor system …

Neuromorphic model of reflex for realtime human-like compliant control of prosthetic hand

CM Niu, Q Luo, C Chou, J Liu, M Hao, N Lan - Annals of Biomedical …, 2021 - Springer
Current control of prosthetic hands is ineffective when grasping deformable, irregular, or
heavy objects. In humans, grasping is achieved under spinal reflexive control of the …

A novel FES strategy for poststroke rehabilitation based on the natural organization of neuromuscular control

VCK Cheung, CM Niu, S Li, Q Xie… - IEEE reviews in …, 2018 - ieeexplore.ieee.org
The past decades have witnessed remarkable progress in neural technologies such as
functional electrical stimulation (FES) and their applications in neurorehabilitation and …

Evaluation of model-based biomimetic control of prosthetic finger force for grasp

Q Luo, CM Niu, J Liu, CH Chou… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Restoring neuromuscular reflex properties in the control of a prosthetic hand may potentially
approach human-level grasp functions in the prosthetic hand. Previous studies have …

Analysis of lower extremity proprioception for anterior cruciate ligament injury prevention: current opinion

T Nagai, ND Schilaty, JD Strauss, EM Crowley… - Sports Medicine, 2018 - Springer
Lower extremity musculoskeletal injuries—such as ACL injury—are common, and the
majority of those injuries occur without external player contact. In order to prevent non …

A biorealistic computational model unfolds human-like compliant properties for control of hand prosthesis

Z Zhang, J Zhang, Q Luo, CH Chou… - IEEE Open Journal …, 2022 - ieeexplore.ieee.org
Objective: Human neuromuscular reflex control provides a biological model for a compliant
hand prosthesis. Here we present a computational approach to understanding the emerging …