The IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring

HJ Marcus, PT Ramirez, DZ Khan, H Layard Horsfall… - Nature medicine, 2024 - nature.com
The next generation of surgical robotics is poised to disrupt healthcare systems worldwide,
requiring new frameworks for evaluation. However, evaluation during a surgical robot's …

Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review

SA Reynolds, L O'Connor, A McGee… - Journal of Cancer …, 2024 - Springer
Purpose Despite clear evidence-based supporting a benefit to exercise on physical and
psychological metrics in patients with cancer, recruitment to exercise trials amongst cancer …

Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial

T Treasure, V Farewell, F Macbeth, K Monson… - Trials, 2019 - Springer
Background Lung metastasectomy in the treatment of advanced colorectal cancer has been
widely adopted without good evidence of survival or palliative benefit. We aimed to test its …

[HTML][HTML] Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET …

E Lim, RA Harris, HE McKeon… - Health Technology …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Lung cancer is the leading cause of cancer death. Surgery remains the
main method of managing early-stage disease. Minimal-access video-assisted …

Intensive triangulation of qualitative research and quantitative data to improve recruitment to randomized trials: the QuinteT approach

L Rooshenas, S Paramasivan… - Qualitative Health …, 2019 - journals.sagepub.com
Randomized controlled trials (RCTs) can provide high quality evidence about the
comparative effectiveness of health care interventions, but many RCTs struggle with or fail to …

Patient and public involvement in research: a journey to co-production

A Price, M Clarke, S Staniszewska, L Chu… - Patient education and …, 2022 - Elsevier
The public and patients can be powerful sensors for shaping and powering healthcare
research. They are joining research teams as investigators and collaborators to co-produce …

Feasibility and safety of radical prostatectomy for oligo‐metastatic prostate cancer: the Testing Radical prostatectomy in men with prostate cancer and oligo …

P Sooriakumaran, C Wilson, I Rombach… - BJU …, 2022 - Wiley Online Library
Objectives To test the feasibility of randomisation to radical prostatectomy (RP) plus pelvic
lymphadenectomy in addition to standard‐of‐care (SOC) systemic therapy in men with …

Study protocol for VIdeo assisted thoracoscopic lobectomy versus conventional Open LobEcTomy for lung cancer, a UK multicentre randomised controlled trial with an …

E Lim, T Batchelor, M Shackcloth, J Dunning… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Lung cancer is a leading cause of cancer deaths worldwide and surgery
remains the main treatment for early stage disease. Prior to the introduction of video …

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) …

E Lim, L Darlison, J Edwards, D Elliott, DA Fennell… - BMJ open, 2020 - bmjopen.bmj.com
Introduction Mesothelioma remains a lethal cancer. To date, systemic therapy with
pemetrexed and a platinum drug remains the only licensed standard of care. As the median …

The challenge of equipoise in trials with a surgical and non-surgical comparison: a qualitative synthesis using meta-ethnography

L Davies, D Beard, JA Cook, A Price, I Osbeck, F Toye - Trials, 2021 - Springer
Background Randomised controlled trials in surgery can be a challenge to design and
conduct, especially when including a non-surgical comparison. As few as half of initiated …