ATP-binding cassette (ABC) transporters make up a superfamily of transmembrane proteins
that play a critical role in the development of drug resistance. This phenomenon is especially …

Vaults are evolutionary highly conserved ribonucleoproteins particles with a hollow barrel-
like structure. The main component of vaults represents the 110 kDa major vault protein …

Abstract Background Cancer-associated fibroblasts (CAFs) play multiple roles in regulating
tumor metastasis and treatment response. Current clinical indicators are insufficient to …

Multidrug resistance (MDR) in cancer is one of the major obstacles of chemotherapy. We
have recently identified a series of 8-hydroxyquinoline Mannich base derivatives with MDR …

This study aimed to clarify the role of multidrug resistance-associated protein 3 (MRP3) in
resistance to neoadjuvant chemoradiotherapy and long-term prognosis of advanced rectal …

The present paper is an update of data on the effects of ionizing radiation (γ-rays, X-rays,
high energy UV, fast neutron) caused by environmental pollution or clinical treatments and …

To examine the possibility of using fractionated radiation in a unique way with molecular
targeted therapy, gene expression profiles of prostate carcinoma cells treated with 10 Gy …

Purpose To understand the molecular mechanisms underlying cancer cell radioresistance,
clinically relevant radioresistant (CRR) cells that continue to proliferate during exposure to 2 …

Post-irradiation residual mass and recurrence always suggest a worse prognosis for
nasopharyngeal carcinoma (NPC). Our study aimed to investigate the malignant behaviors …

Background Chemo-radiotherapy, a combination of chemotherapy and radiotherapy, is the
most frequent treatment for patients with esophageal cancer. In the process of radiotherapy …