Piracetam and piracetam-like drugs

AG Malykh, MR Sadaie - Drugs, 2010 - Springer
There is an increasing interest in nootropic drugs for the treatment of CNS disorders. Since
the last meta-analysis of the clinical efficacy of piracetam, more information has …

[PDF][PDF] The neurobiology of acetyl-L-carnitine

G Traina - Front Biosci (Landmark Ed), 2016 - peirsoncenter.com
1. ABSTRACT A large body of evidence points to the positive effects of dietary
supplementation of acetyl-L-carnitine (ALC). Its use has shown health benefits in …

High-altitude hypoxia induced reactive oxygen species generation, signaling, and mitigation approaches

P Gaur, S Prasad, B Kumar, SK Sharma… - International Journal of …, 2021 - Springer
Homeostasis between pro-oxidants and anti-oxidants is necessary for aerobic life, which if
perturbed and shifted towards pro-oxidants results in oxidative stress. It is generally agreed …

L-carnitine mitigates oxidative stress and disorganization of cytoskeleton intermediate filaments in cisplatin-induced hepato-renal toxicity in rats

A Elkomy, EY Abdelhiee, SE Fadl, MA Emam… - Frontiers in …, 2020 - frontiersin.org
Cisplatin (CP) is one of the most active medications in cancer treatment and has some
adverse effects such as hepatotoxicity and nephrotoxicity. The present research was …

Acetyl‐L‐carnitine‐mediated neuroprotection during hypoxia is attributed to ERK1/2‐Nrf2‐regulated mitochondrial biosynthesis

KB Hota, SK Hota, OP Chaurasia, SB Singh - Hippocampus, 2012 - Wiley Online Library
Neuronal damage in hypoxia and several neurodegenerative disorders is invariably
associated with oxidative damage and mitochondrial dysfunction. Administration of acetyl‐l …

Protective effects of L-carnitine against beta-amyloid-induced memory impairment and anxiety-like behavior in a rat model of Alzheimer's disease

YJ Tork, E Naseri, HS Basir, A Komaki - European Journal of Pharmacology, 2024 - Elsevier
Abstract Alzheimer's disease (AD), the most common cause of dementia, leads to
neurodegeneration and cognitive decline. We investigated the therapeutic effects of L …

[PDF][PDF] The Ameliorative Effects of L-Carnitine against Cisplatin-Induced Gonadal Toxicity in Rats.

AO Sallam, HA Rizk, MA Emam, SE Fadl… - Pakistan Veterinary …, 2021 - bu.edu.eg
The testis plays a vital role in male reproductive function as it secretes testosterone, the male
hormone, and responsible for androgenesis and spermatogenesis (Marty et al., 2003) …

Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS)-induced neuroinflammation by targeting TLR4/NFκB, autophagy, inflammation and …

N Jamali-Raeufy, F Alizadeh, Z Mehrabi… - Metabolic brain …, 2021 - Springer
Acetyl-L-carnitine has been shown to exert neuroprotection against neurodegenerative
diseases. The present study was performed to evaluate neuroprotection effects of acetyl-L …

Bacopa monniera leaf extract ameliorates hypobaric hypoxia induced spatial memory impairment

SK Hota, K Barhwal, I Baitharu, D Prasad… - Neurobiology of …, 2009 - Elsevier
Hypobaric hypoxia induced memory impairment has been attributed to several factors
including increased oxidative stress, depleted mitochondrial bioenergetics, altered …

Carnosine pretreatment protects against hypoxia–ischemia brain damage in the neonatal rat model

X Zhang, L Song, X Cheng, Y Yang, B Luan… - European journal of …, 2011 - Elsevier
Perinatal hypoxia–ischemia brain injury is a major cause of mortality and morbidity in
neonates and lacks an effective treatment thus far. Carnosine has been demonstrated to …