Terpenoids from the medicinal mushroom Antrodia camphorata: Chemistry and medicinal potential

Y Kuang, B Li, Z Wang, X Qiao, M Ye - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to February 2020 Antrodia camphorata is a medicinal mushroom endemic to
Taiwan for the treatment of intoxication, liver injury, cancer, and inflammation. Owing to its …

C2C12 cell model: its role in understanding of insulin resistance at the molecular level and pharmaceutical development at the preclinical stage

CY Wong, H Al-Salami, CR Dass - Journal of Pharmacy and …, 2020 - academic.oup.com
Objectives The myoblast cell line, C2C12, has been utilised extensively in vitro as an
examination model in understanding metabolic disease progression. Although it is …

Curcumae rhizoma and its major constituents against hepatobiliary disease: Pharmacotherapeutic properties and potential clinical applications

TH Gao, W Liao, LT Lin, ZP Zhu, MG Lu, CM Fu, T Xie - Phytomedicine, 2022 - Elsevier
Background Hepatobiliary disease currently serves as an urgent health issue in public due
to health-modulating factors such as extension of life expectancy, increasingly sedentary …

Salvianolic acid C against acetaminophen‐induced acute liver injury by attenuating inflammation, oxidative stress, and apoptosis through inhibition of the Keap1/Nrf2 …

CT Wu, JS Deng, WC Huang, PC Shieh… - Oxidative Medicine …, 2019 - Wiley Online Library
Acetaminophen (APAP) overdose is one of the most common causes of drug‐induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

[HTML][HTML] Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway

J He, Y Yang, F Zhang, Y Li, X Li, X Pu, X He… - Frontiers in …, 2022 - frontiersin.org
Despite the increase in the global prevalence of metabolic dysfunction-associated fatty liver
disease (MAFLD), no approved drug currently exists for the disease. Poria cocos (Schw.) …

[HTML][HTML] Atractylenolide I Ameliorates Acetaminophen-Induced Acute Liver Injury via the TLR4/MAPKs/NF-κB Signaling Pathways

Z Du, Z Ma, S Lai, Q Ding, Z Hu, W Yang… - Frontiers in …, 2022 - frontiersin.org
Background: Acetaminophen (APAP) overdose results in the production of reactive oxygen
species (ROS), induces hepatocyte necrosis, and leads to acute liver failure. Atractylenolide …

The hepatoprotective effect of the probiotic Clostridium butyricum against carbon tetrachloride-induced acute liver damage in mice

J Liu, Y Fu, H Zhang, J Wang, J Zhu, Y Wang, Y Guo… - Food & function, 2017 - pubs.rsc.org
Previous studies have revealed that the probiotic Clostridium butyricum (C. butyricum) can
attenuate cirrhosis in chronic non-alcoholic liver disease. However, the effects of C …

[HTML][HTML] Characterization of Polysaccharides with Antioxidant and Hepatoprotective Activities from the Edible Mushroom Oudemansiella radicata

Q Liu, M Zhu, X Geng, H Wang, TB Ng - Molecules, 2017 - mdpi.com
The preliminary structure, in vitro antioxidant and in vivo hepatoprotective activities of water-
soluble polysaccharides (ORWP) and alkali-soluble polysaccharides (ORAP), prepared from …

[HTML][HTML] Antrodia cinnamomea exerts an anti-hepatoma effect by targeting PI3K/AKT-mediated cell cycle progression in vitro and in vivo

Y Zhang, P Lv, J Ma, N Chen, H Guo, Y Chen… - … Pharmaceutica Sinica B, 2022 - Elsevier
Antrodia cinnamomea is extensively used as a traditional medicine to prevention and
treatment of liver cancer. However, its comprehensive chemical fingerprint is uncertain, and …

[HTML][HTML] Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K …

WP Jiang, JS Deng, SS Huang, SH Wu, CC Chen… - Antioxidants, 2021 - mdpi.com
Liver damage induced by paracetamol overdose is the main cause of acute liver failure
worldwide. In order to study the hepatoprotective effect of Sanghuangporus sanghuang …